Evidence map›Paper›PMID 34440900›Full record

ArticleCells2021

Anti-Inflammatory and Anti-Oxidant Effect of Dimethyl Fumarate in Cystic Fibrosis Bronchial Epithelial Cells.

Onofrio Laselva, Caterina Allegretta, Sante Di Gioia, Carlo Avolio, Massimo Conese

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Evaluation of ATP12A and NFKBIZ as potential markers of inflammatory status in cystic fibrosis airway epithelial cells.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Deleterious effect ofERJ open research · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Cystic Fibrosis and Oxidative Stress: The Role of CFTR.Molecules (Basel, Switzerland) · 2022
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Onofrio LaselvaDepartment of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-0237-4079
Caterina AllegrettaDepartment of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.
Sante Di GioiaDepartment of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0001-7246-5622
Carlo AvolioDepartment of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.
Massimo ConeseDepartment of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0003-3465-6641
University of Foggia · IT

Funding

Università degli Studi di Foggia DR n. 392-2019, Prot. N. 13546 - VII/1, 01/04/2019
6 · The paper itself

Abstract

Cystic Fibrosis (CF) is caused by mutations on the

Indexed as

Anti-Inflammatory AgentsCystic FibrosisDimethyl FumarateEpithelial CellsHumansInterleukin-1betaOxidative StressReactive Oxygen SpeciesTumor Necrosis Factor-alphaAnti-Inflammatory AgentsDimethyl FumarateInterleukin-1betaReactive Oxygen SpeciesTumor Necrosis Factor-alphaairway epithelial cellscystic fibrosiscytokinedimethyl fumarateoxidative stress

Identifiers

PMID34440900
PMCPMC8391758
OpenAlexW3193706569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.