Evidence map›Paper›PMID 34440860›Full record

ArticleCells2021

Comprehensive Integrative Analysis Reveals the Association of

Shweta Arora, Prithvi Singh, Shaniya Ahmad, Tanveer Ahmad, Ravins Dohare, Saleh A Almatroodi, Faris Alrumaihi, Arshad Husain Rahmani, Mansoor Ali Syed

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 44 citations in OpenAlex.

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  18. CAR-macrophage: Breaking new ground in cellular immunotherapy.Frontiers in cell and developmental biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Shweta AroraTranslational Research Lab, Department of Biotechnology, Faculty of Natural Sciences, Jamia Millia Islamia, New Delhi 110025, India.
Prithvi SinghCentre for Interdisciplinary Research in Basic Sciences, Srinivasa Ramanujan Block, Jamia Millia Islamia, New Delhi 110025, India.ORCID 0000-0002-2562-0914
Shaniya AhmadTranslational Research Lab, Department of Biotechnology, Faculty of Natural Sciences, Jamia Millia Islamia, New Delhi 110025, India.ORCID 0000-0001-7388-1740
Tanveer AhmadMultidisciplinary Centre for Advance Research and Studies, Jamia Millia Islamia, New Delhi 110025, India.
Ravins DohareCentre for Interdisciplinary Research in Basic Sciences, Srinivasa Ramanujan Block, Jamia Millia Islamia, New Delhi 110025, India.ORCID 0000-0002-0602-3719
Saleh A AlmatroodiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0000-0002-5260-0265
Faris AlrumaihiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0000-0002-0850-5500
Arshad Husain RahmaniDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.
Mansoor Ali SyedTranslational Research Lab, Department of Biotechnology, Faculty of Natural Sciences, Jamia Millia Islamia, New Delhi 110025, India.ORCID 0000-0003-2697-7832
Department of Biotechnology · INJamia Millia Islamia · INQassim University · SA

Funding

Indian Council of Medical Research 5/3/8/13/ITR-F/2018-ITRIndian Council of Medical Research 5/3/8/57/ITR-F/2019-ITRIndian Council of Medical Research BMI/11(89)/2020Science and Engineering Research Board SB/S2IRJN-199/2014
6 · The paper itself

Abstract

Macrophage polarization and infiltration to the tumor microenvironment (TME) is a critical determining factor for tumor progression. Macrophages are polarized into two states-M1 (pro-inflammatory, anti-tumorigenic and stimulated by LPS or

Indexed as

CarcinogenesisCarcinoma, Non-Small-Cell LungGene Expression Regulation, NeoplasticHumansInterleukin-1betaKruppel-Like Factor 4Kruppel-Like Transcription FactorsLung NeoplasmsMacrophage ActivationMicroRNAsOncogenesPrognosisTumor-Associated MacrophagesTumor MicroenvironmentIL1B protein, mouseInterleukin-1betaKLF4 protein, humanKlf4 protein, mouseKruppel-Like Factor 4Kruppel-Like Transcription FactorsMicroRNAsMIRN34 microRNA, humanIL-1βKLF4macrophage polarizationmiR-34a-5pnon-small cell lung cancer (NSCLC)tumor-associated macrophages (TAMs)tumor microenvironment (TME)

Identifiers

PMID34440860
PMCPMC8392240
OpenAlexW3195948356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.