Evidence map›Paper›PMID 34440837›Full record

ReviewCells2021

MicroRNAs Patterns as Potential Tools for Diagnostic and Prognostic Follow-Up in Cancer Survivorship.

Ilaria Conti, Carolina Simioni, Gabriele Varano, Cinzia Brenna, Eva Costanzi, Luca Maria Neri

Abstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. A new era of cancer immunotherapy: vaccines and miRNAs.Cancer immunology, immunotherapy : CII · 2025
    Review
  3. Role of miRNA in adult ocular tumorigenesis.Frontiers in molecular biosciences · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ilaria ContiDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-7276-3168
Carolina SimioniDepartment of Life Sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy.
Gabriele VaranoDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-3698-4262
Cinzia BrennaDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-1548-3493
Eva CostanziDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-5015-9237
Luca Maria NeriDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in screening methods and pharmacological treatments are increasing the life expectancy of cancer patients. During recent decades, the community of long-term disease-free cancer survivors (LCS) has grown exponentially, raising the issues related to cancer follow-up. Cancer relapse and other cancer-related diseases, as well as lifestyle, influence cancer survival. Recently, the regulatory role of microRNAs (miRNAs) in gene expression and their involvement in human diseases, including cancer, has been identified. Extracellular circulating miRNAs (ECmiRNAs) have been found in biological fluids and specific ECmiRNAs have been associated with cancer development and progression or with a therapy response. Here, we focus on the pivotal role of ECmiRNAs as biomarkers in cancer diagnosis and prognosis. Then, we discuss the relevance of ECmiRNAs expression in cancer survivors for the identification of specific ECmiRNAs profiles as potential tools to assess cancer outcome and to control LCS follow-up.

Indexed as

Antineoplastic AgentsBiomarkers, TumorFollow-Up StudiesGene Expression Regulation, NeoplasticHumansMicroRNAsNeoplasmsPrognosisSurvival AnalysisAntineoplastic AgentsBiomarkers, TumorMicroRNAsbiomarkerscancer prognosislong-cancer survivormicroRNA

Identifiers

PMID34440837
PMCPMC8394126

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.