Evidence map›Paper›PMID 34440731›Full record

ReviewCells2021

Integration of Molecular Information in Risk Assessment of Patients with Myeloproliferative Neoplasms.

Giuseppe G Loscocco, Giacomo Coltro, Paola Guglielmelli, Alessandro M Vannucchi

Abstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Frontiers in genetics · 2023
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giuseppe G LoscoccoCentro di Ricerca e Innovazione Malattie Mieloproliferative (CRIMM), Department of Experimental and Clinical Medicine, Azienda Ospedaliera Universitaria Careggi, University of Florence, Largo Brambilla 3, 50134 Florence, Italy.ORCID 0000-0002-6241-1206
Giacomo ColtroCentro di Ricerca e Innovazione Malattie Mieloproliferative (CRIMM), Department of Experimental and Clinical Medicine, Azienda Ospedaliera Universitaria Careggi, University of Florence, Largo Brambilla 3, 50134 Florence, Italy.
Paola GuglielmelliCentro di Ricerca e Innovazione Malattie Mieloproliferative (CRIMM), Department of Experimental and Clinical Medicine, Azienda Ospedaliera Universitaria Careggi, University of Florence, Largo Brambilla 3, 50134 Florence, Italy.
Alessandro M VannucchiCentro di Ricerca e Innovazione Malattie Mieloproliferative (CRIMM), Department of Experimental and Clinical Medicine, Azienda Ospedaliera Universitaria Careggi, University of Florence, Largo Brambilla 3, 50134 Florence, Italy.

Funding

AIRC 5x1000 called "Metastatic disease: the key unmet need in oncology" to MYNERVA project, 21267PRIN (Progetti di rilevante interesse nazionale)-MIUR called "Myeloid neoplasms: an integrated clinical, molecular and therapeutic approach" 2017WXR72T
6 · The paper itself

Abstract

Philadelphia chromosome-negative myeloproliferative neoplasms (MPN) are clonal disorders of a hematopoietic stem cell, characterized by an abnormal proliferation of largely mature cells driven by mutations in

Indexed as

CalreticulinDioxygenasesDNA-Binding ProteinsHematopoietic Stem Cell TransplantationHumansJanus Kinase 2MutationMyeloproliferative DisordersPrognosisRisk AssessmentSignal TransductionCalreticulinCALR protein, humanDioxygenasesDNA-Binding ProteinsJAK2 protein, humanJanus Kinase 2TET2 protein, humanadditional mutationsCALRessential thrombocythemiaJAK2JAK-STAT pathwayMPLmyelofibrosismyeloproliferative neoplasmspolycythemia veraprognosis

Identifiers

PMID34440731
PMCPMC8391705

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.