Evidence map›Paper›PMID 34440628›Full record

ArticleCells2021

Mitotic Acetylation of Microtubules Promotes Centrosomal

Sylvia Fenosoa Rasamizafy, Claude Delsert, Gabriel Rabeharivelo, Julien Cau, Nathalie Morin, Juliette van Dijk

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sylvia Fenosoa RasamizafyUniversité de Montpellier, 34293 Montpellier, France.ORCID 0000-0002-4785-3567
Claude DelsertUniversité de Montpellier, 34293 Montpellier, France.
Gabriel RabehariveloUniversité de Montpellier, 34293 Montpellier, France.
Julien CauUniversité de Montpellier, 34293 Montpellier, France.
Nathalie MorinUniversité de Montpellier, 34293 Montpellier, France.
Juliette van DijkUniversité de Montpellier, 34293 Montpellier, France.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tubulin post-translational modifications regulate microtubule properties and functions. Mitotic spindle microtubules are highly modified. While tubulin detyrosination promotes proper mitotic progression by recruiting specific microtubule-associated proteins motors, tubulin acetylation that occurs on specific microtubule subsets during mitosis is less well understood. Here, we show that siRNA-mediated depletion of the tubulin acetyltransferase

Indexed as

Protein Processing, Post-TranslationalAcetylationAcetyltransferasesAnimalsCell Cycle ProteinsCentrosomeEpithelial CellsLLC-PK1 CellsMicrotubule ProteinsMicrotubulesMitosisPolo-Like Kinase 1Protein Serine-Threonine KinasesProto-Oncogene ProteinsSignal TransductionSpindle ApparatusAcetyltransferasesCell Cycle ProteinsMicrotubule ProteinsPolo-Like Kinase 1Protein Serine-Threonine KinasesProto-Oncogene Proteinsacetylationacetyltransferase ATAT1centrosomekinetochoremicrotubulesmitosisPLK1 kinasespindle

Identifiers

PMID34440628
PMCPMC8394630
OpenAlexW3187042309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.