Evidence map›Paper›PMID 34440626›Full record

ArticleCells2021

Age-Dependent Distinct Distributions of Dendritic Cells in Autoimmune Dry Eye Murine Model.

Young-Ho Jung, Jin-Suk Ryu, Chang-Ho Yoon, Mee-Kum Kim

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Young-Ho JungDepartment of Ophthalmology, College of Medicine, Seoul National University, 103 Daehak-ro, Jongno-gu, Seoul 03080, Korea.
Jin-Suk RyuLaboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea.
Chang-Ho YoonDepartment of Ophthalmology, College of Medicine, Seoul National University, 103 Daehak-ro, Jongno-gu, Seoul 03080, Korea.ORCID 0000-0003-2203-5709
Mee-Kum KimDepartment of Ophthalmology, College of Medicine, Seoul National University, 103 Daehak-ro, Jongno-gu, Seoul 03080, Korea.ORCID 0000-0001-7850-6894
Seoul National University · KRSeoul National University Hospital · KR

Funding

National Research Foundation of Korea 2020R1F1A1072506Seoul National University Hospital 03-2019-0050
6 · The paper itself

Abstract

We investigated whether aging-dependent changes in dendritic cell (DC) distributions are distinct in autoimmune dry eye compared with an aging-related murine model. Corneal staining and tear secretion were evaluated in young and aged C57BL/6 (B6) and NOD.B10.H2b mice (NOD). In the corneolimbus, lacrimal gland (LG), and mesenteric lymph node (MLN), CD11b

Indexed as

AutoimmunityAge FactorsAnimalsAntigens, CDAutoimmune DiseasesCD11b AntigenCorneaDendritic CellsDisease Models, AnimalDry Eye SyndromesHistocompatibility Antigens Class IIIntegrin alpha ChainsLacrimal ApparatusMaleMiceMice, Inbred C57BLalpha E integrinsAntigens, CDCD11b AntigenHistocompatibility Antigens Class IIIntegrin alpha ChainsItgam protein, mouseagingantigen-presenting cell (APC)autoimmune dry eyeCD103 DCCD11b DCdendritic cells (DCs)MHC-IIhi B cell

Identifiers

PMID34440626
PMCPMC8392312
OpenAlexW3184365601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.