Evidence map›Paper›PMID 34440571›Full record

ArticleLife (Basel, Switzerland)2021

Validation of Chemokine Biomarkers in Duchenne Muscular Dystrophy.

Michael Ogundele, Jesslyn S Zhang, Mansi V Goswami, Marissa L Barbieri, Utkarsh J Dang, James S Novak, Eric P Hoffman, Kanneboyina Nagaraju, Cinrg-Dnhs Investigators, Yetrib Hathout

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Michael OgundeleDepartment of Pharmaceutical Science, School of Pharmacy and Pharmaceutical Sciences, Binghamton University-SUNY, Johnson City, NY 13790, USA.
Jesslyn S ZhangDepartment of Pharmaceutical Science, School of Pharmacy and Pharmaceutical Sciences, Binghamton University-SUNY, Johnson City, NY 13790, USA.
Mansi V GoswamiDepartment of Pharmaceutical Science, School of Pharmacy and Pharmaceutical Sciences, Binghamton University-SUNY, Johnson City, NY 13790, USA.
Marissa L BarbieriDepartment of Pharmaceutical Science, School of Pharmacy and Pharmaceutical Sciences, Binghamton University-SUNY, Johnson City, NY 13790, USA.
Utkarsh J DangDepartment of Health Sciences, Carleton University, Ottawa, ON K1S 5B6, Canada.
James S NovakCenter for Genetic Medicine Research, Children's Research Institute, Children's National Hospital, Washington, DC 20010, USA.
Eric P HoffmanDepartment of Pharmaceutical Science, School of Pharmacy and Pharmaceutical Sciences, Binghamton University-SUNY, Johnson City, NY 13790, USA.
Kanneboyina NagarajuDepartment of Pharmaceutical Science, School of Pharmacy and Pharmaceutical Sciences, Binghamton University-SUNY, Johnson City, NY 13790, USA.
Cinrg-Dnhs Investigators
Yetrib HathoutDepartment of Pharmaceutical Science, School of Pharmacy and Pharmaceutical Sciences, Binghamton University-SUNY, Johnson City, NY 13790, USA.
Binghamton University · USCarleton University · CAChildren's National · US

Funding

Dissociation of efficacy from side effects of anti-inflammatory therapies in Duchenne muscular dystrophyP50HD090254 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VAN DEN ANKER, JOHANNES NICOLAAS · 2019 to 2020
$1.6M
Clinically Meaningful Outcomes for Duchenne Muscular Dystrophy Therapeutic TrialsR01AR061875 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MCDONALD, CRAIG M. · 2011 to 2014
$1.3M
NIAMS NIH HHS R01 AR061875NIH HHS P50HD090254U.S. Department of Defense W81XWH-16-1-0557
6 · The paper itself

Abstract

Duchenne muscular dystrophy (DMD) is a progressive muscle disease involving complex skeletal muscle pathogenesis. The pathogenesis is triggered by sarcolemma instability due to the lack of dystrophin protein expression, leading to Ca

Indexed as

Becker muscular dystrophychemokinesdisease severityDuchenne muscular dystrophyinflammatory biomarkersvalidation studies

Identifiers

PMID34440571
PMCPMC8401931
OpenAlexW3195713222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.