Evidence map›Paper›PMID 34440544›Full record

ReviewLife (Basel, Switzerland)2021

Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3',5' Cyclic Nucleotide Precursors.

Judit E Šponer, Jiří Šponer, Aleš Kovařík, Ondrej Šedo, Zbyněk Zdráhal, Giovanna Costanzo, Ernesto Di Mauro

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Judit E ŠponerInstitute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 61265 Brno, Czech Republic.ORCID 0000-0001-5794-2873
Jiří ŠponerInstitute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 61265 Brno, Czech Republic.
Aleš KovaříkInstitute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 61265 Brno, Czech Republic.ORCID 0000-0003-2896-0698
Ondrej ŠedoCentral European Institute of Technology, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.ORCID 0000-0002-5091-2978
Zbyněk ZdráhalCentral European Institute of Technology, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Giovanna CostanzoInstitute of Molecular Biology and Pathology, CNR, Piazzale A. Moro 5, 00185 Rome, Italy.
Ernesto Di MauroInstitute of Molecular Biology and Pathology, CNR, Piazzale A. Moro 5, 00185 Rome, Italy.

Funding

European Regional Development Fund CZ.02.1.01/0.0/0.0/ 15_003/0000477
6 · The paper itself

Abstract

Template-free nonenzymatic polymerization of 3',5' cyclic nucleotides is an emerging topic of the origin of life research. In the last ten years, a number of papers have been published addressing various aspects of this process. These works evoked a vivid discussion among scientists working in the field of prebiotic chemistry. The aim of the current review is to answer the most frequently raised questions related to the detection and characterization of oligomeric products as well as to the geological context of this chemistry.

Indexed as

cyclic nucleotidespolymerizationprebiotic chemistry

Identifiers

PMID34440544
PMCPMC8400769

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.