Evidence map›Paper›PMID 34440535›Full record

ArticleLife (Basel, Switzerland)2021

Skeletal Effects of Bone-Targeted TGFbeta Inhibition in a Mouse Model of Duchenne Muscular Dystrophy.

Juliana Marulanda, Iris Boraschi-Diaz, Pierre Beauparlant, Philippe Crine, Frank Rauch

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Aging and cancer: current understandings and future perspectives.Signal transduction and targeted therapy · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Juliana MarulandaShriners Hospital for Children-Canada, Montreal, QC H4A 0A9, Canada.
Iris Boraschi-DiazShriners Hospital for Children-Canada, Montreal, QC H4A 0A9, Canada.
Pierre BeauparlantPreciThera Inc., Montreal, QC H3A 2R7, Canada.
Philippe CrinePreciThera Inc., Montreal, QC H3A 2R7, Canada.
Frank RauchShriners Hospital for Children-Canada, Montreal, QC H4A 0A9, Canada.
Shriners Hospitals for Children - Canada · CAMcGill University · CA

Funding

Jesse's Journey 2017-12Shriners Hospitals for Children 84060-CAN-13
6 · The paper itself

Abstract

Duchenne muscular dystrophy (DMD) is a severe progressive muscle disease that is frequently associated with secondary osteoporosis. Previous studies have shown that TGFbeta inactivating antibody improves the muscle phenotype in

Indexed as

bone remodelingDuchenne muscular dystrophyfracturestransforming growth factor beta

Identifiers

PMID34440535
PMCPMC8401157
OpenAlexW3189243995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.