Evidence map›Paper›PMID 34440527›Full record

ReviewLife (Basel, Switzerland)2021

Physical Activity and Bone Vascularization: A Way to Explore in Bone Repair Context?

Rkia Wazzani, Stéphane Pallu, Céline Bourzac, Saïd Ahmaïdi, Hugues Portier, Christelle Jaffré

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Molecular mechanisms of exercise contributing to tissue regeneration.Signal transduction and targeted therapy · 2022
    Review
  9. Role of Traditional Chinese Medicine in Bone Regeneration and Osteoporosis.Frontiers in bioengineering and biotechnology · 2022
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Rkia WazzaniLaboratoire APERE, Université de Picardie Jules Verne, CEDEX, F-80000 Amiens, France.
Stéphane PalluLaboratoire B3OA, Université de Paris, CEDEX, F-75010 Paris, France.
Céline BourzacLaboratoire B3OA, Université de Paris, CEDEX, F-75010 Paris, France.ORCID 0000-0002-4922-1010
Saïd AhmaïdiLaboratoire APERE, Université de Picardie Jules Verne, CEDEX, F-80000 Amiens, France.
Hugues PortierLaboratoire B3OA, Université de Paris, CEDEX, F-75010 Paris, France.ORCID 0000-0003-3328-3257
Christelle JaffréLaboratoire APERE, Université de Picardie Jules Verne, CEDEX, F-80000 Amiens, France.
Adaptation physiologiques à l'exercice et réadaptation à l'effort · FRUniversité d'Orléans · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity is widely recognized as a biotherapy by WHO in the fight and prevention of bone diseases such as osteoporosis. It reduces the risk of disabling fractures associated with many comorbidities, and whose repair is a major public health and economic issue. Bone tissue is a dynamic supportive tissue that reshapes itself according to the mechanical stresses to which it is exposed. Physical exercise is recognized as a key factor for bone health. However, the effects of exercise on bone quality depend on exercise protocols, duration, intensity, and frequency. Today, the effects of different exercise modalities on capillary bone vascularization, bone blood flow, and bone angiogenesis remain poorly understood and unclear. As vascularization is an integral part of bone repair process, the analysis of the preventive and/or curative effects of physical exercise is currently very undeveloped. Angiogenesis-osteogenesis coupling may constitute a new way for understanding the role of physical activity, especially in fracturing or in the integration of bone biomaterials. Thus, this review aimed to clarify the link between physical activities, vascularization, and bone repair.

Indexed as

angiogenesisbone repairbone vascularizationphysical activityVEGF

Identifiers

PMID34440527
PMCPMC8399402
OpenAlexW3187243916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.