Evidence map›Paper›PMID 34440515›Full record

ArticleLife (Basel, Switzerland)2021

Prevalence of Bladder and Bowel Dysfunction in Duchenne Muscular Dystrophy Using the Childhood Bladder and Bowel Dysfunction Questionnaire.

Judith M Lionarons, Imelda J M de Groot, Johanna M Fock, Sylvia Klinkenberg, Desiree M J Vrijens, Anita C E Vreugdenhil, Evita G Medici-van den Herik, Inge Cuppen, Bregje Jaeger, Erik H Niks and 6 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Observational
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 2 countries.

Judith M LionaronsDepartment of Neurology, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands.
Imelda J M de GrootDepartment of Rehabilitation Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Johanna M FockDepartment of Neurology, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Sylvia KlinkenbergDepartment of Neurology, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands.
Desiree M J VrijensDepartment of Urology, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands.
Anita C E VreugdenhilDepartment of Pediatrics, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands.
Evita G Medici-van den HerikDepartment of Neurology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Inge CuppenDepartment of Neurology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
Bregje JaegerDepartment of Neurology, Amsterdam University Medical Center, 1105 AZ Amsterdam, The Netherlands.
Erik H NiksDuchenne Center Netherlands, 2333 ZA Leiden, The Netherlands.ORCID 0000-0001-5892-5143
Rinske HoogerhuisYouth Healthcare Center South Limburg, 6411 TE Heerlen, The Netherlands.
Nicky Platte-van AttekumYouth Healthcare Center South Limburg, 6411 TE Heerlen, The Netherlands.
Frans J M FeronDepartment of Social Medicine, Maastricht University, 6229 ER Maastricht, The Netherlands.
Catharina G FaberDepartment of Neurology, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands.
Jos G M HendriksenDuchenne Center Netherlands, 2333 ZA Leiden, The Netherlands.
Johan S H VlesSchool for Mental Health and Neuroscience, Maastricht University, 6229 ER Maastricht, The Netherlands.
Maastricht University · NLGGD Zuid Limburg · NLAmsterdam University Medical Centers · NLDuchenne Parent Project · NLErasmus MC · NLLeiden University Medical Center · NLRadboud University Nijmegen · NLUniversity Medical Center Groningen · NLUniversity Medical Center Utrecht · NL

Funding

Duchenne Parent Project grant 2016 on non-motor problems in DuchenneStichting Spieren voor Spieren SvS15-
6 · The paper itself

Abstract

introductionLower urinary tract symptoms (LUTS) and gastrointestinal (GI) problems are common in Duchenne muscular dystrophy (DMD), but not systematically assessed in regular care. We aimed to determine the prevalence of bladder and bowel dysfunction (BBD) in DMD patients compared with healthy controls (HC).

methodsThe Childhood Bladder and Bowel Dysfunction Questionnaire (CBBDQ) based on the International Rome III criteria and the International Children's Continence Society was filled out by 57 DMD patients and 56 HC. Additionally, possible associations of BBD with, for example, medication use or quality of life were evaluated in an additional questionnaire developed by experts.

resultsIn 74% of patients versus 56% of HC ≥ 1 LUTS (n.s.) were reported, 68% of patients versus 39% of HC reported ≥1 bowel symptom (

conclusionsThese data underscore that standard screening for BBD is needed and that the CBBDQ could be of added value to optimize DMD care.

Indexed as

bladder and bowel dysfunctionconstipationDuchenne muscular dystrophylower urinary tract symptomsurinary incontinence

Identifiers

PMID34440515
PMCPMC8399211
OpenAlexW3189929035

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.