Evidence map›Paper›PMID 34440493›Full record

ArticleLife (Basel, Switzerland)2021

Steroidal Saponins Isolated from the Rhizome of

Shinya Okubo, Tomoe Ohta, Yukihiro Shoyama, Takuhiro Uto

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. The anti-cancer activity of Dioscin: an update and future perspective.Medical oncology (Northwood, London, England) · 2025
    Review
  2. Article
  3. Article
  4. Molecules (Basel, Switzerland) · 2023
    Review
  5. Review
  6. Article
  7. Article
  8. [Palmitic acid suppresses autophagy in neonatal rat cardiomyocytesNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shinya OkuboGraduate School of Pharmaceutical Sciences, Nagasaki International University, 2825-7 Huis Ten Bosch-Cho, Sasebo, Nagasaki 859-3298, Japan.
Tomoe OhtaGraduate School of Pharmaceutical Sciences, Nagasaki International University, 2825-7 Huis Ten Bosch-Cho, Sasebo, Nagasaki 859-3298, Japan.
Yukihiro ShoyamaGraduate School of Pharmaceutical Sciences, Nagasaki International University, 2825-7 Huis Ten Bosch-Cho, Sasebo, Nagasaki 859-3298, Japan.
Takuhiro UtoGraduate School of Pharmaceutical Sciences, Nagasaki International University, 2825-7 Huis Ten Bosch-Cho, Sasebo, Nagasaki 859-3298, Japan.
Nagasaki International University · JP

Funding

Japan Science Society 2018-4039Japan Society for the Promotion of Science 19K07145Japan Society for the Promotion of Science 25871011
6 · The paper itself

Abstract

Our preliminary screening identified an extract from the rhizome of

Indexed as

autophagyBeclin 1dioscinDioscorea tokorohepatocellular carcinomaHepG2Kampo medicinesLC3-IIp62steroidal saponins

Identifiers

PMID34440493
PMCPMC8400091
OpenAlexW3184480642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.