Evidence map›Paper›PMID 34440473›Full record

ReviewLife (Basel, Switzerland)2021

Neuroimaging Studies of Nonsuicidal Self-Injury in Youth: A Systematic Review.

Marcelo J A A Brañas, Marcos S Croci, Ana Beatriz Ravagnani Salto, Victoria F Doretto, Eduardo Martinho, Marcos Macedo, Euripedes C Miguel, Leonardo Roever, Pedro M Pan

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marcelo J A A BrañasNational Institute of Developmental Psychiatry for Children and Adolescents (INPD), São Paulo 05403-903, Brazil.ORCID 0000-0003-3218-7327
Marcos S CrociNational Institute of Developmental Psychiatry for Children and Adolescents (INPD), São Paulo 05403-903, Brazil.ORCID 0000-0002-0743-2565
Ana Beatriz Ravagnani SaltoNational Institute of Developmental Psychiatry for Children and Adolescents (INPD), São Paulo 05403-903, Brazil.
Victoria F DorettoNational Institute of Developmental Psychiatry for Children and Adolescents (INPD), São Paulo 05403-903, Brazil.
Eduardo MartinhoDepartment of Psychiatry, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-903, Brazil.
Marcos MacedoLaboratory of Integrative Neurosciences (LiNC), Universidade Federal de São Paulo, São Paulo 04021-001, Brazil.
Euripedes C MiguelNational Institute of Developmental Psychiatry for Children and Adolescents (INPD), São Paulo 05403-903, Brazil.
Leonardo RoeverNational Institute of Developmental Psychiatry for Children and Adolescents (INPD), São Paulo 05403-903, Brazil.
Pedro M PanNational Institute of Developmental Psychiatry for Children and Adolescents (INPD), São Paulo 05403-903, Brazil.ORCID 0000-0002-1943-6520

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 465550/2014-2Fundação de Amparo à Pesquisa do Estado de São Paulo 2014/50917-0
6 · The paper itself

Abstract

Nonsuicidal self-injury (NSSI) is prevalent and affects mainly the youth population. It is prospectively associated with suicide attempts, making it a target for suicide prevention. Recently, several studies have investigated neural pathways of NSSI using neuroimaging. However, there is a lack of systematized appraisal of these findings. This systematic review aims to identify and summarize the main neuroimaging findings of NSSI in youth. We followed PRISMA statement guidelines and searched MEDLINE, APA PsycInfo, and Google Scholar databases for neuroimaging studies, irrespective of imaging modality, specifically investigating NSSI in samples with a mean age of up to 25 years old. Quality assessment was made using the Newcastle-Ottawa and Joanna Briggs Institute scales. The initial search retrieved 3030 articles; 21 met inclusion criteria, with a total of 938 subjects. Eighteen studies employed functional neuroimaging techniques such as resting-state and task-based fMRI (emotional, interpersonal exposure/social exclusion, pain, reward, and cognitive processing paradigms). Three studies reported on structural MRI. An association of NSSI behavior and altered emotional processing in cortico-limbic neurocircuitry was commonly reported. Additionally, alterations in potential circuits involving pain, reward, interpersonal, self-processing, and executive function control processes were identified. NSSI has complex and diverse neural underpinnings. Future longitudinal studies are needed to understand its developmental aspects better.

Indexed as

fMRIJBI Critical Appraisal ChecklistneuroimagingNewcastle–Ottawa Scalenonsuicidal self-injuryNSSIself-harmself-mutilationsystematic reviewyouth

Identifiers

PMID34440473
PMCPMC8399885

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.