Evidence map›Paper›PMID 34440461›Full record

ArticleGenes2021

Evolution and Functional Characteristics of the Novel

Shouxiang Sun, Yumei Wang, Pei-Tian Goh, Mónica Lopes-Marques, L Filipe C Castro, Óscar Monroig, Meng-Kiat Kuah, Xiaojuan Cao, Alexander Chong Shu-Chien, Jian Gao

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Shouxiang SunKey Lab of Freshwater Animal Breeding, College of Fisheries, Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China.
Yumei WangKey Lab of Freshwater Animal Breeding, College of Fisheries, Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China.
Pei-Tian GohCenter for Chemical Biology, Universiti Sains Malaysia, Bayan Lepas 11800, Penang, Malaysia.ORCID 0000-0002-1947-0550
Mónica Lopes-MarquesCIIMAR/CIMAR-Interdisciplinary Center of Marine and Environmental Research, University of Porto, 4099002 Porto, Portugal.ORCID 0000-0002-8597-4730
L Filipe C CastroCIIMAR/CIMAR-Interdisciplinary Center of Marine and Environmental Research, University of Porto, 4099002 Porto, Portugal.ORCID 0000-0001-7697-386X
Óscar MonroigInstituto de Acuicultura Torre de la Sal (IATS-CSIC), Ribera de Cabanes, 12595 Castellon, Spain.
Meng-Kiat KuahCenter for Chemical Biology, Universiti Sains Malaysia, Bayan Lepas 11800, Penang, Malaysia.ORCID 0000-0001-6654-7680
Xiaojuan CaoKey Lab of Freshwater Animal Breeding, College of Fisheries, Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China.
Alexander Chong Shu-ChienCenter for Chemical Biology, Universiti Sains Malaysia, Bayan Lepas 11800, Penang, Malaysia.ORCID 0000-0003-3014-442X
Jian GaoKey Lab of Freshwater Animal Breeding, College of Fisheries, Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China.
Huazhong Agricultural University · CNUniversiti Sains Malaysia · MYUniversidade do Porto · PTInstituto de Acuicultura Torre de la Sal · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elongation of very long-chain fatty acid (Elovl) proteins are key enzymes that catalyze the rate-limiting step in the fatty acid elongation pathway. The most recently discovered member of the Elovl family, Elovl8, has been proposed to be a fish-specific elongase with two gene paralogs described in teleosts. However, the biological functions of Elovl8 are still to be elucidated. In this study, we showed that in contrast to previous findings,

Indexed as

Evolution, MolecularAnimalsCloning, MolecularCRISPR-Cas SystemsFatty Acid ElongasesFatty AcidsFatty Acids, UnsaturatedFish ProteinsGene Expression Regulation, EnzymologicLipogenesisZebrafishFatty Acid ElongasesFatty AcidsFatty Acids, UnsaturatedFish Proteinselovl8fatty acid synthesisgene knockoutzebrafish

Identifiers

PMID34440461
PMCPMC8392482
OpenAlexW3195828277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.