Evidence map›Paper›PMID 34440442›Full record

ArticleGenes2021

Variants Affecting the C-Terminal Tail of UNC93B1 Are Not a Common Risk Factor for Systemic Lupus Erythematosus.

Sarah Kiener, Camillo Ribi, Irene Keller, Carlo Chizzolini, Marten Trendelenburg, Uyen Huynh-Do, Johannes von Kempis, On Behalf Of Swiss Sle Cohort Study Sscs, Tosso Leeb

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Sarah KienerInstitute of Genetics, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.ORCID 0000-0002-2714-2370
Camillo RibiDivision of Immunology and Allergy, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), 1011 Lausanne, Switzerland.ORCID 0000-0002-0446-9741
Irene KellerInterfaculty Bioinformatics Unit, University of Bern, 3012 Bern, Switzerland.
Carlo ChizzoliniDepartment of Pathology and Immunology, School of Medicine, Geneva University, 1211 Geneva, Switzerland.ORCID 0000-0003-4849-6335
Marten TrendelenburgLaboratory for Clinical Immunology, Department of Biomedicine and Division of Internal Medicine, University Hospital of Basel, 4031 Basel, Switzerland.
Uyen Huynh-DoDivision of Nephrology and Hypertension, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.ORCID 0000-0002-7276-032X
Johannes von KempisDivision of Rheumatology, Cantonal Hospital St. Gallen, 9007 St. Gallen, Switzerland.
On Behalf Of Swiss Sle Cohort Study Sscs
Tosso LeebInstitute of Genetics, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.ORCID 0000-0003-0553-4880
University of Bern · CHKantonsspital St. Gallen · CHUniversity Hospital of Basel · CHUniversity Hospital of Bern · CHUniversity of Geneva · CHUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is a heterogeneous multifactorial disease. Upregulated TLR7 signaling is a known risk factor for SLE. Recently, it was shown that specific genetic variants in

Indexed as

Genetic Predisposition to DiseaseAdultAutoimmune DiseasesFemaleHumansLupus Erythematosus, SystemicMaleMembrane Transport ProteinsMiddle AgedRisk FactorsSignal TransductionToll-Like Receptor 7Membrane Transport ProteinsTLR7 protein, humanToll-Like Receptor 7UNC93B1 protein, humanautoimmunitycandidate geneHomo sapiensimmunologyTLR7 signaling

Identifiers

PMID34440442
PMCPMC8392493
OpenAlexW3194922835

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.