Evidence map›Paper›PMID 34440426›Full record

ArticleGenes2021

Elana Meer, Vivian L Qin, Harini V Gudiseva, Brendan McGeehan, Rebecca Salowe, Maxwell Pistilli, Jie He, Ebenezer Daniel, Gui Shang Ying, Venkata R M Chavali and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Glaucoma Animal Models beyond Chronic IOP Increase.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Elana MeerPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Vivian L QinScheie Eye Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Harini V GudisevaScheie Eye Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Brendan McGeehanScheie Eye Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Rebecca SaloweScheie Eye Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Maxwell PistilliScheie Eye Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Jie HeScheie Eye Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Ebenezer DanielScheie Eye Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Gui Shang YingScheie Eye Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Venkata R M ChavaliScheie Eye Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-3439-3490
Joan M O'BrienScheie Eye Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Penn Presbyterian Medical Center · USUniversity of Pennsylvania · US

Funding

Scientific TransparencyP30EY001583 · NEI · UNIVERSITY OF PENNSYLVANIA · PI Qi N Cui · 1985 to 2026
$19.5M
Primary Open Angle African-American Glaucoma Genetics Study RenewalR01EY023557 · NEI · UNIVERSITY OF PENNSYLVANIA · PI O'BRIEN, JOAN M · 2014 to 2025
$18.1M
NEI NIH HHS P30 EY001583NEI NIH HHS R01 EY023557
6 · The paper itself

Abstract

Primary open-angle glaucoma (POAG) is the leading cause of irreversible blindness worldwide and has been associated with multiple genetic risk factors. The

Indexed as

Genetic Predisposition to DiseaseAdultAgedBlack or African AmericanFemaleGenome-Wide Association StudyGenotypeGlaucoma, Open-AngleHumansIntraocular PressureLIM-Homeodomain ProteinsMaleMiddle AgedPolymorphism, Single NucleotideRisk FactorsTranscription FactorsLIM homeobox transcription factor 1 betaLIM-Homeodomain ProteinsTranscription FactorsAfrican AmericangeneticglaucomaLMX1Bprimary open-angle glaucoma

Identifiers

PMID34440426
PMCPMC8394298
OpenAlexW3193666088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.