Evidence map›Paper›PMID 34440337›Full record

ArticleGenes2021

Genome-Wide Association Study Using Whole-Genome Sequence Data for Fertility, Health Indicator, and Endoparasite Infection Traits in German Black Pied Cattle.

Manuel J Wolf, Tong Yin, Guilherme B Neumann, Paula Korkuć, Gudrun A Brockmann, Sven König, Katharina May

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Manuel J WolfInstitute of Animal Breeding and Genetics, Justus-Liebig-University of Gießen, 35390 Gießen, Germany.
Tong YinInstitute of Animal Breeding and Genetics, Justus-Liebig-University of Gießen, 35390 Gießen, Germany.
Guilherme B NeumannAlbrecht Daniel Thaer-Institute for Agricultural and Horticultural Sciences, Animal Breeding Biology and Molecular Genetics, Humboldt-Universität of Berlin, 10115 Berlin, Germany.ORCID 0000-0001-6581-3019
Paula KorkućAlbrecht Daniel Thaer-Institute for Agricultural and Horticultural Sciences, Animal Breeding Biology and Molecular Genetics, Humboldt-Universität of Berlin, 10115 Berlin, Germany.
Gudrun A BrockmannAlbrecht Daniel Thaer-Institute for Agricultural and Horticultural Sciences, Animal Breeding Biology and Molecular Genetics, Humboldt-Universität of Berlin, 10115 Berlin, Germany.
Sven KönigInstitute of Animal Breeding and Genetics, Justus-Liebig-University of Gießen, 35390 Gießen, Germany.
Katharina MayInstitute of Animal Breeding and Genetics, Justus-Liebig-University of Gießen, 35390 Gießen, Germany.ORCID 0000-0001-7809-1385
Justus-Liebig-Universität Gießen · DEHumboldt-Universität zu Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This genome-wide association study (GWAS) aimed to identify sequence variants (SVs) and candidate genes associated with fertility and health in endangered German Black Pied cattle (DSN) based on whole-genome sequence (WGS) data. We used 304 sequenced DSN cattle for the imputation of 1797 genotyped DSN to WGS. The final dataset included 11,413,456 SVs of 1886 cows. Cow traits were calving-to-first service interval (CTFS), non-return after 56 days (NR56), somatic cell score (SCS), fat-to-protein ratio (FPR), and three pre-corrected endoparasite infection traits. We identified 40 SVs above the genome-wide significance and suggestive threshold associated with CTFS and NR56, and three important potential candidate genes (

Indexed as

AnimalsCattleCattle DiseasesFertilityGenome-Wide Association StudyParasitic Diseases, AnimalWhole Genome Sequencingcandidate genescomplex traitsdairy cowsdual-purpose cattleendangered breedendoparasite resistanceGWAS

Identifiers

PMID34440337
PMCPMC8391191
OpenAlexW3185926863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.