Evidence map›Paper›PMID 34440285›Full record

ArticleGenes2021

Molecular Characterization of Choroideremia-Associated Deletions Reveals an Unexpected Regulation of

Tiziana Fioretti, Valentina Di Iorio, Barbara Lombardo, Francesca De Falco, Armando Cevenini, Fabio Cattaneo, Francesco Testa, Lucio Pastore, Francesca Simonelli, Gabriella Esposito

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. De Novo Large Deletions in theDiagnostics (Basel, Switzerland) · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Tiziana FiorettiCEINGE-Biotecnologie Avanzate s.c. a r.l., Via G. Salvatore 486, 80145 Naples, Italy.
Valentina Di IorioEye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania Luigi Vanvitelli, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-8179-5970
Barbara LombardoCEINGE-Biotecnologie Avanzate s.c. a r.l., Via G. Salvatore 486, 80145 Naples, Italy.ORCID 0000-0003-3884-1043
Francesca De FalcoCEINGE-Biotecnologie Avanzate s.c. a r.l., Via G. Salvatore 486, 80145 Naples, Italy.
Armando CeveniniCEINGE-Biotecnologie Avanzate s.c. a r.l., Via G. Salvatore 486, 80145 Naples, Italy.ORCID 0000-0002-1858-2833
Fabio CattaneoDepartment of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-5833-8333
Francesco TestaEye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania Luigi Vanvitelli, Via S. Pansini 5, 80131 Naples, Italy.
Lucio PastoreCEINGE-Biotecnologie Avanzate s.c. a r.l., Via G. Salvatore 486, 80145 Naples, Italy.ORCID 0000-0001-6894-9317
Francesca SimonelliEye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania Luigi Vanvitelli, Via S. Pansini 5, 80131 Naples, Italy.
Gabriella EspositoCEINGE-Biotecnologie Avanzate s.c. a r.l., Via G. Salvatore 486, 80145 Naples, Italy.ORCID 0000-0002-4255-7312
Ceinge Biotecnologie Avanzate (Italy) · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Choroideremia (CHM) is a X-linked recessive chorioretinal dystrophy due to deficiency of the

Indexed as

Gene DeletionTranscription, GeneticAdaptor Proteins, Signal TransducingAdultAgedChoroideremiaFemaleGene Expression RegulationHumansMaleMiddle AgedAdaptor Proteins, Signal TransducingCHM protein, humanCHMchoroideremiadeletion breakpointinherited retinal degenerationREP1REP2repeat elementstranscriptional regulation

Identifiers

PMID34440285
PMCPMC8392058
OpenAlexW3185723897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.