Evidence map›Paper›PMID 34440271›Full record

ReviewBiomedicines2021

Sharing the Same Perspective. Mental Disorders and Central Serous Chorioretinopathy: A Systematic Review of Evidence from 2010 to 2020.

Gianluca Pandolfo, Giovanni Genovese, Antonio Bruno, Diletta Palumbo, Umberto Poli, Sebastiano Gangemi, Pasquale Aragona, Alessandro Meduri

Abstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gianluca PandolfoDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, 98121 Messina, Italy.
Giovanni GenoveseDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, 98121 Messina, Italy.ORCID 0000-0002-4984-7208
Antonio BrunoDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, 98121 Messina, Italy.ORCID 0000-0002-8789-1680
Diletta PalumboDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, 98121 Messina, Italy.
Umberto PoliDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, 98121 Messina, Italy.
Sebastiano GangemiSchool and Operative Unit of Allergy and Clinical Immunology, Policlinico "G. Martino", Department of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy.
Pasquale AragonaDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, 98121 Messina, Italy.
Alessandro MeduriDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, 98121 Messina, Italy.ORCID 0000-0001-7546-9178

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relevance of the association between mental disorders and other conditions might have been underestimated due to its complexity. Central Serous Chorioretinopathy (CSC) is an ophthalmological disorder associated with many psychiatric factors. The aim of this systematic review is to evaluate the association between mental disorders and CSC.

methodsArticles about studies performed on humans on CSC published in peer-reviewed journals from 1 January 2010 to 31 December 2020 were included in the review.

resultsWe selected 21 research papers. Nine studies measured stress and anxious depressive symptoms, which are associated with CSC onset and recurrences, emerging as a state marker of the disease. Four out of the five studies focused on sleep disorders suggested a reliable association with CSC. Four studies evaluated other various psychiatric factors. The role of psychopharmacological medication has still not been elucidated (three studies).

conclusionMultiple pieces of evidence highlights that CSC might arise in the context of systemic disease. This notion, together with the increasing evidence supporting a link between psychiatric disorders and choroidal thickness, suggests that CSC and mental disorders may share some etiopathogenetic pathways. Further research is needed to better investigate possible common etiopathogenetic pathways, especially vascular, immunological and endocrinological systems.

Indexed as

central serous chorioretinopathyinsomniamental disordersneuroinflammationpsychiatry

Identifiers

PMID34440271
PMCPMC8394052

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.