Evidence map›Paper›PMID 34440264›Full record

ArticleBiomedicines2021

Oviductal Telocytes in Patients with Uterine Myoma.

Veronika Aleksandrovych, Anna Wrona, Tomasz Bereza, Kazimierz Pityński, Krzysztof Gil

Abstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Scleroderma-like Impairment in the Network of Telocytes/CD34International journal of molecular sciences · 2021
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Veronika AleksandrovychDepartment of Pathophysiology, Jagiellonian University Medical College, 31-121 Krakow, Poland.ORCID 0000-0001-9850-6269
Anna WronaGynecology and Obstetrics Ward with Gynecologic Oncology Subdivision, J.Śniadecki's Specialistic Hospital, 33-300 Nowy Sącz, Poland.
Tomasz BerezaDepartment of Anatomy, Jagiellonian University Medical College, 31-034 Krakow, Poland.
Kazimierz PityńskiDepartment of Gynecology and Oncology, Jagiellonian University Medical College, 31-501 Krakow, Poland.
Krzysztof GilDepartment of Pathophysiology, Jagiellonian University Medical College, 31-121 Krakow, Poland.ORCID 0000-0002-4732-7698

Funding

the National Science Center, Poland 2017/25/N/NZ4/01965
6 · The paper itself

Abstract

Tubal factor infertility occurs in 30-35% of infertile pairs and may be caused by impaired muscular contractility and ciliary beating as well as immunological imbalance and chronic inflammation. Newly discovered telocytes (TCs) have a wide palette of features, which play a role in oviduct physiology. We have observed tissue samples from human fallopian tubes in patients with and without uterine myoma by immunolabelling. According to the immunohistochemical co-expression of markers, it has been determined that TCs are engaged in a wide range of physiological processes, including local innervation, sensitivity to hypoxia, regulation of calcium, and sex steroid hormones balances. Due to the proximity of NOS- and ChAT-positive nerve fibers and the expression of ion channels markers, tubal TCs might be considered conductor cells. Additionally, their integration in contractions and cilia physiology in the context of fertility has been revealed. We have observed the difference in telocytes expression in the human oviduct between groups of patients and attempted to describe this population of cells specifically in the case of infertility development, a clinically relevant avenue for further studies.

Indexed as

CD34infertilitymuscular contractilityoviductPDGFRαtelocytes

Identifiers

PMID34440264
PMCPMC8391874

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.