Evidence map›Paper›PMID 34440231›Full record

ReviewBiomedicines2021

How Are Adenosine and Adenosine A

Akihisa Mori, Brittany Cross, Shinichi Uchida, Jill Kerrick Walker, Robert Ristuccia

Abstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. The Pharmacological Potential of Adenosine AMolecules (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Akihisa MoriKyowa Kirin Co., Ltd., Otemachi, Chiyoda-ku, Tokyo 100-0004, Japan.
Brittany CrossKyowa Kirin, Inc., Bedminster, NJ 07921, USA.
Shinichi UchidaKyowa Kirin Co., Ltd., Otemachi, Chiyoda-ku, Tokyo 100-0004, Japan.
Jill Kerrick WalkerKyowa Kirin, Inc., Bedminster, NJ 07921, USA.
Robert RistucciaKyowa Kirin, Inc., Bedminster, NJ 07921, USA.

Funding

Kyowa Kirin n/a
6 · The paper itself

Abstract

Adenosine is extensively distributed in the central and peripheral nervous systems, where it plays a key role as a neuromodulator. It has long been implicated in the pathogenesis of progressive neurogenerative disorders such as Parkinson's disease, and there is now growing interest in its role in amyotrophic lateral sclerosis (ALS). The motor neurons affected in ALS are responsive to adenosine receptor function, and there is accumulating evidence for beneficial effects of adenosine A

Indexed as

adenosineadenosine A2A receptoramyotrophic lateral sclerosis

Identifiers

PMID34440231
PMCPMC8392384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.