ArticleBiomedicines2021
A Proposal for Practical Diagnosis of Renal Hypouricemia: Evidenced from Genetic Studies of Nonfunctional Variants of
Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 8 citations in OpenAlex.
- A case of renal hypouricemia type 1 associated with compound heterozygous URAT1/SLC22A12 variants A209V and F379L: clinical evidence for their pathogenic significance.CEN case reports · 2026Article
- Genotype-Informed Characterization of Mild Renal Hypouricemia.Kidney international reports · 2026Article
- Dysuricemia.Biomedicines · 2023Review
- Clinical features suggesting renal hypouricemia as the cause of acute kidney injury: a case report and review of the literature.Journal of nephrology · 2023Review
- Vitamin C transporter SVCT1 serves a physiological role as a urate importer: functional analyses and in vivo investigations.Pflugers Archiv : European journal of physiology · 2023Article
- Genetic Basis of the Epidemiological Features and Clinical Significance of Renal Hypouricemia.Biomedicines · 2022Review
- Analysis of Purine Metabolism to Elucidate the Pathogenesis of Acute Kidney Injury in Renal Hypouricemia.Biomedicines · 2022Article
- Hypouricemia and Urate Transporters.Biomedicines · 2022Review
- Identification of a dysfunctional exon-skipping splice variant inFrontiers in genetics · 2022Article
- OAT10/SLC22A13 Acts as a Renal Urate Re-Absorber: Clinico-Genetic and Functional Analyses With Pharmacological Impacts.Frontiers in pharmacology · 2022Article
Corrections and comments
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Authors and funding
26 authors at 8 institutions in 1 country.
Funding
Abstract
backgroundRenal hypouricemia (RHUC) is characterized by a low serum uric acid (SUA) level and high fractional excretion of uric acid (FE
methodsIn 30,685 Japanese health-examination participants, we genotyped the two most common nonfunctional variants of
resultsFrequency of hypouricemic individuals (SUA ≤ 3.0 mg/dL) was 0.97% (male) and 6.94% (female) among 30,685 participants. High frequencies of those having at least one allele of NFV-
conclusionsOur findings reveal that specific patterns of FE
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