Evidence map›Paper›PMID 34440145›Full record

ReviewBiomedicines2021

Pediatric Psoriasis: From New Insights into Pathogenesis to Updates on Treatment.

Hye One Kim, Seok Young Kang, Jin Cheol Kim, Chun Wook Park, Bo Young Chung

Abstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Long-term safety and efficacy of secukinumab in paediatric severe plaque psoriasis: 236-week, Phase 3 trial results.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hye One KimDepartment of Dermatology, Hallym University Kangnam Sacred Heart Hospital, Seoul 07441, Korea.ORCID 0000-0001-5846-0008
Seok Young KangDepartment of Dermatology, Hallym University Kangnam Sacred Heart Hospital, Seoul 07441, Korea.ORCID 0000-0001-6532-2244
Jin Cheol KimDepartment of Dermatology, Hallym University Kangnam Sacred Heart Hospital, Seoul 07441, Korea.ORCID 0000-0002-1523-6951
Chun Wook ParkDepartment of Dermatology, Hallym University Kangnam Sacred Heart Hospital, Seoul 07441, Korea.ORCID 0000-0003-4512-8668
Bo Young ChungDepartment of Dermatology, Hallym University Kangnam Sacred Heart Hospital, Seoul 07441, Korea.ORCID 0000-0002-2795-0140

Funding

National Research Foundation of Korea 2021R1F1A1059510
6 · The paper itself

Abstract

Psoriasis is a chronic inflammatory systemic disease primarily affecting the skin, but which often involves considerable comorbidities as well. One-third of psoriasis cases start during childhood. In pediatric psoriasis, an association with several medical comorbidities is also indicated. Furthermore, because of its chronic nature and frequent relapses, psoriatic patients tend to require long-term treatment and experience negative impacts on their quality of life. Considering the different clinical characteristics of pediatric psoriasis, it has recently been presented that the pathogenesis of pediatric psoriasis is distinct from adult psoriasis. Treatment for pediatric psoriasis usually involves the same methods as for adults. However, most treatments in pediatric psoriasis are used off-label and research in this regard is still lacking. Targeted therapies involving newly developed biologics are also increasingly being applied to psoriasis in children. This review summarizes the clinical characteristics of pediatric psoriasis and focuses mainly on the updated concepts of pathogenesis and treatments in pediatric psoriasis. This was undertaken to widen the understanding of these relevant aspects and to provide better management of pediatric psoriasis by clinicians.

Indexed as

biologicschildhoodpathogenesispediatricpsoriasissystemic treatmenttopical treatment

Identifiers

PMID34440145
PMCPMC8393839

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.