Evidence map›Paper›PMID 34440070›Full record

ArticleBiomedicines2021

Synergistic AHR Binding Pathway with EMT Effects on Serous Ovarian Tumors Recognized by Multidisciplinary Integrated Analysis.

Kuo-Min Su, Hong-Wei Gao, Chia-Ming Chang, Kai-Hsi Lu, Mu-Hsien Yu, Yi-Hsin Lin, Li-Chun Liu, Chia-Ching Chang, Yao-Feng Li, Cheng-Chang Chang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kuo-Min SuGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0001-7366-3671
Hong-Wei GaoDepartment of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.
Chia-Ming ChangSchool of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0001-6172-9741
Kai-Hsi LuDepartment of Medical Research and Education, Cheng-Hsin General Hospital, Taipei 112, Taiwan.
Mu-Hsien YuGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.
Yi-Hsin LinDepartment of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.
Li-Chun LiuDepartment of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0001-7022-8316
Chia-Ching ChangDepartment of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.
Yao-Feng LiDepartment of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0001-9601-8149
Cheng-Chang ChangGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0002-7356-446X
Tri-Service General Hospital · TWCheng Hsin General Hospital · TW

Funding

Ministry of Science and Technology, Taiwan MOST 110-2321-B-016-002the Veterans General Hospital, Tri-Service General Hospital and Academia Sinica Joint Research Programs VTA110-T-4-1Tri-Service General Hospital TSGH-D-109189, TSGH-D-109203, TSGH-D-110136, TSGH-D-110172 and TSGH-E-110230
6 · The paper itself

Abstract

Epithelial ovarian cancers (EOCs) are fatal and obstinate among gynecological malignancies in advanced stage or relapsed status, with serous carcinomas accounting for the vast majority. Unlike EOCs, borderline ovarian tumors (BOTs), including serous BOTs, maintain a semimalignant appearance. Using gene ontology (GO)-based integrative analysis, we analyzed gene set databases of serous BOTs and serous ovarian carcinomas for dysregulated GO terms and pathways and identified multiple differentially expressed genes (DEGs) in various aspects. The

Indexed as

aryl hydrocarbon receptorborderline ovarian tumorsdifferentially expressed genesepithelial–mesenchymal transitionepithelial ovarian cancersgene ontologyintegrative analysis

Identifiers

PMID34440070
PMCPMC8389648
OpenAlexW3183228486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.