Evidence map›Paper›PMID 34439998›Full record

ReviewBiology2021

Epigenetics for Crop Improvement in Times of Global Change.

Ioanna Kakoulidou, Evangelia V Avramidou, Miroslav Baránek, Sophie Brunel-Muguet, Sara Farrona, Frank Johannes, Eirini Kaiserli, Michal Lieberman-Lazarovich, Federico Martinelli, Velimir Mladenov and 3 more

Abstract readReview
In one paragraph

Review in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Linking cellular metabolism to chromatin modifications in plants.Journal of integrative plant biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ioanna KakoulidouDepartment of Molecular Life Sciences, Technical University of Munich, Liesel-Beckmann-Str. 2, 85354 Freising, Germany.
Evangelia V AvramidouLaboratory of Forest Genetics and Biotechnology, Institute of Mediterranean Forest Ecosystems, Hellenic Agricultural Organization-Dimitra (ELGO-DIMITRA), 11528 Athens, Greece.ORCID 0000-0002-5932-1189
Miroslav BaránekFaculty of Horticulture, Mendeleum-Institute of Genetics, Mendel University in Brno, Valtická 334, 69144 Lednice, Czech Republic.ORCID 0000-0002-1583-3588
Sophie Brunel-MuguetUMR 950 Ecophysiologie Végétale, Agronomie et Nutritions N, C, S, UNICAEN, INRAE, Normandie Université, CEDEX, F-14032 Caen, France.
Sara FarronaPlant and AgriBiosciences Centre, Ryan Institute, National University of Ireland (NUI) Galway, H91 TK33 Galway, Ireland.
Frank JohannesDepartment of Molecular Life Sciences, Technical University of Munich, Liesel-Beckmann-Str. 2, 85354 Freising, Germany.
Eirini KaiserliInstitute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, Bower Building, University of Glasgow, Glasgow G12 8QQ, UK.ORCID 0000-0003-1517-4591
Michal Lieberman-LazarovichInstitute of Plant Sciences, Agricultural Research Organization, Volcani Center, Rishon LeZion 7505101, Israel.
Federico MartinelliDepartment of Biology, University of Florence, 50019 Sesto Fiorentino, Italy.ORCID 0000-0002-8502-767X
Velimir MladenovFaculty of Agriculture, University of Novi Sad, Sq. Dositeja Obradovića 8, 21000 Novi Sad, Serbia.ORCID 0000-0002-2182-6579
Pilar S TestillanoPollen Biotechnology of Crop Plants Group, Centro de Investigaciones Biológicas Margarita Salas-(CIB-CSIC), Ramiro Maeztu 9, 28040 Madrid, Spain.ORCID 0000-0003-4509-7646
Valya VassilevaDepartment of Molecular Biology and Genetics, Institute of Plant Physiology and Genetics, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str., Bldg. 21, 1113 Sofia, Bulgaria.ORCID 0000-0002-9055-8002
Stéphane MauryLaboratoire de Biologie des Ligneux et des Grandes Cultures, INRAE, EA1207 USC1328, Université d'Orléans, F-45067 Orléans, France.ORCID 0000-0003-0481-0847

Funding

European Cooperation in Science and Technology CA19125
6 · The paper itself

Abstract

Epigenetics has emerged as an important research field for crop improvement under the on-going climatic changes. Heritable epigenetic changes can arise independently of DNA sequence alterations and have been associated with altered gene expression and transmitted phenotypic variation. By modulating plant development and physiological responses to environmental conditions, epigenetic diversity-naturally, genetically, chemically, or environmentally induced-can help optimise crop traits in an era challenged by global climate change. Beyond DNA sequence variation, the epigenetic modifications may contribute to breeding by providing useful markers and allowing the use of epigenome diversity to predict plant performance and increase final crop production. Given the difficulties in transferring the knowledge of the epigenetic mechanisms from model plants to crops, various strategies have emerged. Among those strategies are modelling frameworks dedicated to predicting epigenetically controlled-adaptive traits, the use of epigenetics for in vitro regeneration to accelerate crop breeding, and changes of specific epigenetic marks that modulate gene expression of traits of interest. The key challenge that agriculture faces in the 21st century is to increase crop production by speeding up the breeding of resilient crop species. Therefore, epigenetics provides fundamental molecular information with potential direct applications in crop enhancement, tolerance, and adaptation within the context of climate change.

Indexed as

breedingclimate changeDNA methylationepigenomicsmemoryplant epigeneticsprediction modelspriming

Identifiers

PMID34439998
PMCPMC8389687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.