Evidence map›Paper›PMID 34439979›Full record

ArticleBiology2021

Profiling Human

Laura Martínez-Alarcón, Sergio Liarte, Juan J Quereda, Aida Sáez-Acosta, Carlos de Torre-Minguela, Livia Mendonça, Juana M Abellaneda, María J Majado, Antonio Ríos, Pablo Ramírez and 2 more

Abstract read
In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Laura Martínez-AlarcónServicio de Cirugía, Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar, 30120 Murcia, Spain.
Sergio LiarteLaboratorio de Medicina Regenerativa, Oncología Molecular y TGFβ, Instituto Murciano de Investigación Biosanitaria, 30120 Murcia, Spain.ORCID 0000-0003-1004-4982
Juan J QueredaDepartamento Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, 46115 Valencia, Spain.ORCID 0000-0002-1105-9505
Aida Sáez-AcostaGrupo de Investigación Cría y Salud Animal, Universidad de Murcia, 30100 Murcia, Spain.
Carlos de Torre-MinguelaUnidad de Inflamación y Cirugía Experimental, Instituto Murciano de Investigación Biosanitaria, 30120 Murcia, Spain.ORCID 0000-0003-3314-3203
Livia MendonçaEscola de Vetérinaria, Universidade Federal de Goiás, Goiánia 74001-970, Brazil.ORCID 0000-0002-4900-5334
Juana M AbellanedaGrupo de Investigación Cría y Salud Animal, Universidad de Murcia, 30100 Murcia, Spain.
María J MajadoServicio de Hematología, Hospital Clínico Universitario Virgen de la Arrixaca, 30120 Murcia, Spain.
Antonio RíosServicio de Cirugía, Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar, 30120 Murcia, Spain.ORCID 0000-0001-5512-9010
Pablo RamírezServicio de Cirugía, Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar, 30120 Murcia, Spain.
Antonio MuñozInstituto Murciano de Investigación Biosanitaria, 30120 Murcia, Spain.
Guillermo RamisInstituto Murciano de Investigación Biosanitaria, 30120 Murcia, Spain.

Funding

Fundación Séneca 12037/PI/09
6 · The paper itself

Abstract

Xenotransplantation of pig organs receives substantial attention for being comparable to human's. However, compatibility constraints involving hyper-acute rejection (HAR) still block clinical applications. Transgenesis of human complement regulatory proteins has been proposed to overcome xenorejection. Pigs expressing human-

Indexed as

gene expressionhCD55RTCAtransgenic pigsxenotransplantation

Identifiers

PMID34439979
PMCPMC8389641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.