Evidence map›Paper›PMID 34439947›Full record

ArticleBiology2021

The Influence of Sexual Behavior and Demographic Characteristics in the Expression of HPV-Related Biomarkers in a Colposcopy Population of Reproductive Age Greek Women.

George Valasoulis, Abraham Pouliakis, Georgios Michail, Athina-Ioanna Daponte, Georgios Galazios, Ioannis G Panayiotides, Alexandros Daponte

Abstract read
In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

George ValasoulisDepartment of Obstetrics & Gynaecology, University Hospital of Larisa, 41334 Larisa, Greece.ORCID 0000-0003-4444-3711
Abraham PouliakisSecond Department of Pathology, National and Kapodistrian University of Athens, Attikon University Hospital, 12462 Athens, Greece.ORCID 0000-0002-0074-3619
Georgios MichailDepartment of Obstetrics & Gynaecology, University Hospital of Patras, 26504 Patras, Greece.ORCID 0000-0003-3555-8867
Athina-Ioanna DaponteDepartment of Obstetrics & Gynaecology, University Hospital of Larisa, 41334 Larisa, Greece.
Georgios GalaziosDepartment of Obstetrics & Gynaecology, University Hospital of Alexandroupolis, 68100 Alexandroupolis, Greece.
Ioannis G PanayiotidesSecond Department of Pathology, National and Kapodistrian University of Athens, Attikon University Hospital, 12462 Athens, Greece.
Alexandros DaponteDepartment of Obstetrics & Gynaecology, University Hospital of Larisa, 41334 Larisa, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the significant scientific evolution in primary and secondary cervical cancer prevention in the battle started by George Papanicolaou in the previous century, global cervical cancer mortality rates remain disappointing. The widespread implementation of HPV-related molecular markers has paved the way to tremendous developments in cervical cancer screening, with the transition from cytological approach to the more accurate and cost-effective HPV testing modalities. However, the academic audience and different health systems have not yet adopted a universal approach in screening strategies, and even artificial intelligence modalities have been utilized from the multidisciplinary scientific armamentarium. Combination algorithms, scoring systems as well as artificial intelligent models have been so far proposed for cervical screening and management. The impact of sexual lifestyle inherently possesses a key role in the prevalence of HPV-related biomarkers. This study aimed to investigate any possible influence of sexual behavior and demographic characteristics in the expression of HPV-related biomarkers in a colposcopy population from October 2016 to June 2017, and corroborated the determining role of age at fist intercourse; the older the age, the lower the probability for DNA positivity. Multivariate analysis illustrated additionally that a number of sexual partners exceeding 4.2 was crucial, with women with ≤5 partners being approximately four times less likely to harbor a positive HPV DNA test (

Indexed as

biomarkersCINcolposcopycondomsHPVHPV DNAhuman papillomaviruslifestylemRNA E6 and E7

Identifiers

PMID34439947
PMCPMC8389230

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.