Evidence map›Paper›PMID 34439938›Full record

ArticleBiology2021

Vitamin D Is Necessary for Murine Gastric Epithelial Homeostasis.

Ifrah Ismail Ali, Iltaf Shah, Sayed Marzouk, Sherif M Karam, Asma Al Menhali

Abstract read
In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ifrah Ismail AliDepartment of Biology, College of Science, United Arab Emirates University, Al Ain 15551, United Arab Emirates.
Iltaf ShahDepartment of Chemistry, College of Science, United Arab Emirates University, Al Ain 15551, United Arab Emirates.ORCID 0000-0002-3739-6083
Sayed MarzoukDepartment of Chemistry, College of Science, United Arab Emirates University, Al Ain 15551, United Arab Emirates.
Sherif M KaramDepartment of Anatomy, College of Medicine & Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab Emirates.ORCID 0000-0002-8590-3975
Asma Al MenhaliDepartment of Biology, College of Science, United Arab Emirates University, Al Ain 15551, United Arab Emirates.ORCID 0000-0001-5081-561X

Funding

Zayed Center for Health Sciences, United Arab Emirates University UAEU, Center-Based Interdisciplinary (grant number 31R138)
6 · The paper itself

Abstract

Unlike other organs, the importance of VD in a normal stomach is unknown. This study focuses on understanding the physiological role of vitamin D in gastric epithelial homeostasis. C57BL/6J mice were divided into three groups that were either fed a standard diet and kept in normal light/dark cycles (SDL), fed a standard diet but kept in the dark (SDD) or fed a vitamin D-deficient diet and kept in the dark (VDD). After 3 months, sera were collected to measure vitamin D levels by LC-MS/MS, gastric tissues were collected for immunohistochemical and gene expression analyses and gastric contents were collected to measure acid levels. The VDD group showed a significant decrease in the acid-secreting parietal cell-specific genes

Indexed as

cell differentiationcell proliferationgastric epithelial homeostasisvitamin D3vitamin D receptor

Identifiers

PMID34439938
PMCPMC8389223

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.