BICD Cargo Adaptor 1 (BICD1) Downregulation Correlates with a Decreased Level of PD-L1 and Predicts a Favorable Prognosis in Patients with IDH1-Mutant Lower-Grade Gliomas.

Shang-Pen Huang, Chien-Hsiu Li, Wei-Min Chang, Yuan-Feng Lin

Abstract read

In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Shang-Pen HuangCenter of General Education, Chung Hua University, Hsinchu 707, Taiwan.

Chien-Hsiu LiGenomics Research Center, Academia Sinica, Taipei 11529, Taiwan.

Wei-Min ChangSchool of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-6899-4043

Yuan-Feng LinGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0003-4456-0766

Funding

Ministry of Science and Technology, Taiwan MOST 108-2320-B-038-017-MY3

6 · The paper itself

Abstract

Although several biomarkers have been identified to predict the prognosis of lower-grade (Grade II/III) gliomas (LGGs), we still need to identify new markers to facilitate those well-known markers to obtain more accurate prognosis prediction in LGGs. Bioinformatics data from The Cancer Genome Atlas (TCGA), the Chinese Glioma Genome Atlas (CGGA), and the Cancer Cell Line Encyclopedia (CCLE) datasets were used as the research materials. In total, 34 genes associated with the HIF1A pathway were analyzed using the hierarchical method to search for the most compatible gene. The BICD cargo adaptor 1 (BICD1) gene (

Indexed as

BICD1biomarkerlower-grade gliomasPD-L1prognosis

Identifiers

PMID34439934

DOI10.3390/biology10080701

PMCPMC8389329

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.