Evidence map›Paper›PMID 34439919›Full record

ArticleBiomolecules2021

Transcriptional Regulation of

Marjorie Buist, David Fuss, Mojgan Rastegar

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  11. The Chromatin Structure at theInternational journal of molecular sciences · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marjorie BuistDepartment of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
David FussDepartment of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Mojgan RastegarDepartment of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.ORCID 0000-0003-3619-6116
University of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methyl CpG binding protein 2 (MeCP2) is the main DNA methyl-binding protein in the brain that binds to 5-methylcytosine and 5-hydroxymethyl cytosine.

Indexed as

Gene Expression RegulationAnimalsBrainBrain-Derived Neurotrophic FactorCell LineDNA MethylationGene Expression ProfilingHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMedulloblastomaMetforminMethyl-CpG-Binding Protein 2MiceMice, TransgenicMutationProtein IsoformsBDNF protein, humanBrain-Derived Neurotrophic FactorHydroxymethylglutaryl-CoA Reductase InhibitorsMECP2 protein, humanMetforminMethyl-CpG-Binding Protein 2Protein IsoformsRNARNA, RibosomalSimvastatinBDNFDaoy medulloblastoma cellsDNA methylationMeCP2MECP2E1MECP2E2MeCP2 isoformsmetforminRett Syndromeribosomal RNAsimvastatinstatinstranscription

Identifiers

PMID34439919
PMCPMC8391797
OpenAlexW3194946931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.