Evidence map›Paper›PMID 34439917›Full record

ArticleBiomolecules2021

Computational Insights into the Structural Dynamics of MDA5 Variants Associated with Aicardi-Goutières Syndrome and Singleton-Merten Syndrome.

Vijayakumar Gosu, Santanu Sasidharan, Prakash Saudagar, Hak-Kyo Lee, Donghyun Shin

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Overlap Diagnostic Odyssey and Full Mouth Rehabilitation of a Juvenile Patient With IFIH1-Related Disorder: A Case of Aicardi-Goutières and Singleton Merten Syndromes Overlap.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Vijayakumar GosuDepartment of Animal Biotechnology, Jeonbuk National University, Jeonju 54896, Korea.
Santanu SasidharanDepartment of Biotechnology, National Institute of Technology, Warangal 506004, Telangana, India.ORCID 0000-0002-0204-0263
Prakash SaudagarDepartment of Biotechnology, National Institute of Technology, Warangal 506004, Telangana, India.
Hak-Kyo LeeDepartment of Animal Biotechnology, Jeonbuk National University, Jeonju 54896, Korea.
Donghyun ShinDepartment of Agricultural Convergence Technology, Jeonbuk National University, Jeonju 54896, Korea.ORCID 0000-0002-0819-0553
Jeonbuk National University · KRNational Institute of Technology Warangal · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanoma differentiation-associated protein 5 (MDA5) is a crucial RIG-I-like receptor RNA helicase enzyme encoded by

Indexed as

MutationAortic DiseasesAutoimmune Diseases of the Nervous SystemComputational BiologyDental Enamel HypoplasiaHumansHydrogen BondingInterferon-Induced Helicase, IFIH1MetacarpusMolecular ConformationMolecular Dynamics SimulationMuscular DiseasesMutant ProteinsMutation, MissenseNervous System MalformationsOdontodysplasiaIFIH1 protein, humanInterferon-Induced Helicase, IFIH1Mutant ProteinsRNAAicardi–Goutières syndromeIFIH1melanoma differentiation-associated protein 5molecular dynamic simulationSingleton–Merten syndrome

Identifiers

PMID34439917
PMCPMC8393256
OpenAlexW3194388063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.