ReviewBiomolecules2021
Cytokine Storms in the Course of COVID-19 and Haemophagocytic Lymphohistiocytosis in Pregnant and Postpartum Women.
Review in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Necrotizing myometritis following vaginal delivery complicated by retained placenta and uterine artery embolization: A case report.SAGE open medical case reports · 2025Article
- Sex differences in pneumonia risk during COVID-19 in Mexico.Scientific reports · 2024Article
- Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- ICOS-ICOSL pathway enhances NKT-like cell antiviral function in pregnant women with COVID-19.International journal of medical sciences · 2024Article
- Stress of Prematurity in the Experience of the COVID-19 Pandemic-Current State of Knowledge.Life (Basel, Switzerland) · 2023Review
- Review
- Assessing Biomarkers in Viral Infection.Advances in experimental medicine and biology · 2023Review
- Knowledge, Attitudes, and Practices towards COVID-19 among Pregnant Women in Northern Bangladesh: A Community-Based Cross-Sectional Study.Behavioral sciences (Basel, Switzerland) · 2022Article
- Pregnancy and COVID-19.Journal of clinical medicine · 2022Review
- Prevalence of COVID-19 in Different Types of Collagen Vascular Diseases and its Relationship with Drugs Used in these Patients.Mediterranean journal of rheumatology · 2022Article
- Changes in the Gut Microbiome and Pathologies in Pregnancy.International journal of environmental research and public health · 2022Review
- Neonatal COVID and Familial Hemophagocytic Lymphohistiocytosis.Pediatric emergency care · 2022Article
- Case report and literature review: Hemophagocytic lymphohistiocytosis in a pregnant woman with systemic lupus erythematosus withFrontiers in oncology · 2022Article
- Role of Dexamethasone and Methylprednisolone Corticosteroids in Coronavirus Disease 2019 Hospitalized Patients: A Review.Frontiers in microbiology · 2022Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The term 'cytokine storm' (CS) applies to a pathological autoimmune reaction when the interactions that lead to cytokine production are destabilised and may even lead to death. CS may be induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In this study, we present our analysis of certain pathological processes that induce a CS in pregnant and postpartum women. We draw our attention to the similarities between the severe course of Coronavirus Disease 2019 (COVID-19) and haemophagocytic lymphohistiocytosis (HLH). It is noteworthy that many of the criteria used to diagnose HLH are described as COVID-19 mortality predictors. Cytokine storms are considered to be an important cause of death in patients with the severe course of SARS-CoV-2 infection. Due to the fact that pregnant women are in an immunosuppressive state, viral pulmonary infections are more perilous for them-possible risks include miscarriage, intrauterine growth restriction or birth before the term; sometimes ventilation support is needed. HLH should be considered in pregnant and puerperal women suffering from moderately severe to severe COVID-19 and presenting with: fever unresponsive to antibiotic therapy, cytopenia, hepatitis and hyperferritinaemia. The HLH disorder is rare and difficult to diagnose; however, its early detection could reduce patient mortality.
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