Evidence map›Paper›PMID 34439790›Full record

ArticleBiomolecules2021

Pancreatic Progenitor Commitment Is Marked by an Increase in Ink4a/Arf Expression.

Elena Montano, Alessandra Pollice, Valeria Lucci, Geppino Falco, Ornella Affinito, Girolama La Mantia, Maria Vivo, Tiziana Angrisano

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Identification ofGenes · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Elena MontanoDepartment of Biology, University of Naples "Federico II", 80147 Naples, Italy.
Alessandra PolliceDepartment of Biology, University of Naples "Federico II", 80147 Naples, Italy.
Valeria LucciDepartment of Biology, University of Naples "Federico II", 80147 Naples, Italy.
Geppino FalcoDepartment of Biology, University of Naples "Federico II", 80147 Naples, Italy.ORCID 0000-0001-6193-7233
Ornella AffinitoIRCCS SDN, 80143 Naples, Italy.
Girolama La MantiaDepartment of Biology, University of Naples "Federico II", 80147 Naples, Italy.
Maria VivoDepartment of Chemistry and Biology, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0003-2458-4226
Tiziana AngrisanoDepartment of Biology, University of Naples "Federico II", 80147 Naples, Italy.ORCID 0000-0002-5940-5278
University of Naples Federico II · ITCentro di Riferimento Oncologico della Basilicata · ITSDN Istituto di Ricerca Diagnostica e Nucleare · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The identification of the molecular mechanisms controlling early cell fate decisions in mammals is of paramount importance as the ability to determine specific lineage differentiation represents a significant opportunity for new therapies. Pancreatic Progenitor Cells (PPCs) constitute a regenerative reserve essential for the maintenance and regeneration of the pancreas. Besides, PPCs represent an excellent model for understanding pathological pancreatic cellular remodeling. Given the lack of valid markers of early endoderm, the identification of new ones is of fundamental importance. Both products of the

Indexed as

Epigenesis, GeneticGene ExpressionAnimalsBiomarkersCell DifferentiationCell LineageCyclin-Dependent Kinase Inhibitor p16Genetic LociHepatocyte Nuclear Factor 3-betaHepatocyte Nuclear Factor 6Homeodomain ProteinsInsulin-Secreting CellsIntercellular Signaling Peptides and ProteinsMiceMouse Embryonic Stem CellsNanog Homeobox ProteinBiomarkersCyclin-Dependent Kinase Inhibitor p16Foxa2 protein, mouseHepatocyte Nuclear Factor 3-betaHepatocyte Nuclear Factor 6Homeodomain ProteinsIntercellular Signaling Peptides and ProteinsNanog Homeobox ProteinNanog protein, mousenephrocan protein, mouseNkx6-1 protein, mouseOctamer Transcription Factor-3Onecut1 protein, mousepancreatic and duodenal homeobox 1 proteinPou5f1 protein, mouseTrans-ActivatorsARFCdkn2aembryonic stem cellsINK4aPancreatic Progenitor Cells

Identifiers

PMID34439790
PMCPMC8392192
OpenAlexW3191505475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.