Evidence map›Paper›PMID 34439784›Full record

ArticleBiomolecules2021

Clinically Applicable Cyclotron-Produced Gallium-68 Gives High-Yield Radiolabeling of DOTA-Based Tracers.

Emma Jussing, Stefan Milton, Erik Samén, Mohammad Mahdi Moein, Lovisa Bylund, Rimma Axelsson, Jonathan Siikanen, Thuy A Tran

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Comparison ofProstate cancer and prostatic diseases · 2024
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  6. Rapid fabrication and dissolution of pressedEJNMMI radiopharmacy and chemistry · 2025
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  8. Development of a versatile [Frontiers in chemistry · 2024
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  9. Microfluidic-based production of [EJNMMI radiopharmacy and chemistry · 2023
    Article
  10. Article
  11. Fully automated radiolabeling of [EJNMMI radiopharmacy and chemistry · 2023
    Article
  12. Article
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  14. Good practices forEJNMMI radiopharmacy and chemistry · 2022
    Review
  15. Analysis of Pros and Cons in Using [Molecules (Basel, Switzerland) · 2022
    Article
  16. Cold Kit Labeling: The Future ofFrontiers in medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Emma JussingDepartment of Oncology and Pathology, Karolinska Instituted, SE-171 77 Stockholm, Sweden.
Stefan MiltonDepartment of Oncology and Pathology, Karolinska Instituted, SE-171 77 Stockholm, Sweden.
Erik SaménDepartment of Oncology and Pathology, Karolinska Instituted, SE-171 77 Stockholm, Sweden.
Mohammad Mahdi MoeinDepartment of Oncology and Pathology, Karolinska Instituted, SE-171 77 Stockholm, Sweden.
Lovisa BylundDepartment of Radiopharmacy, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.
Rimma AxelssonDepartment of Medical Radiation Physics and Nuclear Medicine, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.
Jonathan SiikanenDepartment of Oncology and Pathology, Karolinska Instituted, SE-171 77 Stockholm, Sweden.
Thuy A TranDepartment of Oncology and Pathology, Karolinska Instituted, SE-171 77 Stockholm, Sweden.
Karolinska Institutet · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

By using solid targets in medical cyclotrons, it is possible to produce large amounts of

Indexed as

AcetatesAscorbic AcidChelating AgentsCyclotronsEthylenediaminesGalliumGallium RadioisotopesHeterocyclic Compounds, 1-RingHumansIsotope LabelingOctreotidePositron-Emission TomographyQuinolinesRadiochemistry1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid1,4,7-triazacyclononane-N,N',N''-triacetic acidAcetatesAscorbic AcidChelating AgentsEdotreotideEthylenediaminesFAPI-46GalliumGallium-68gallium chlorideGallium RadioisotopesHeterocyclic Compounds, 1-RingN,N'-di(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acidOctreotideQuinolinesascorbatecyclotron-produced gallium-68DOTA chelatorDOTATOCFAPI-46

Identifiers

PMID34439784
PMCPMC8393313
OpenAlexW3192906491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.