Evidence map›Paper›PMID 34439750›Full record

ArticleBiomolecules2021

The Right-Handed Parallel β-Helix Topology of

Jessica Guillerm, Jean-Marie Frère, Filip Meersman, André Matagne

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jessica GuillermCentre for Protein Engineering, Laboratory of Enzymology and Protein Folding, InBioS, University of Liège, Building B6C, Quartier Agora, Allée du 6 Août, 13, 4000 Liège, Sart-Tilman, Belgium.
Jean-Marie FrèreCentre for Protein Engineering, Laboratory of Enzymology and Protein Folding, InBioS, University of Liège, Building B6C, Quartier Agora, Allée du 6 Août, 13, 4000 Liège, Sart-Tilman, Belgium.ORCID 0000-0001-8280-9783
Filip MeersmanDepartment of Chemistry, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
André MatagneCentre for Protein Engineering, Laboratory of Enzymology and Protein Folding, InBioS, University of Liège, Building B6C, Quartier Agora, Allée du 6 Août, 13, 4000 Liège, Sart-Tilman, Belgium.
University of Liège · BEUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complex topologies of large multi-domain globular proteins make the study of their folding and assembly particularly demanding. It is often characterized by complex kinetics and undesired side reactions, such as aggregation. The structural simplicity of tandem-repeat proteins, which are characterized by the repetition of a basic structural motif and are stabilized exclusively by sequentially localized contacts, has provided opportunities for dissecting their folding landscapes. In this study, we focus on the

Indexed as

Amino Acid MotifsCarboxylic Ester HydrolasesCircular DichroismDickeya chrysanthemiHydrogen-Ion ConcentrationKineticsLinear ModelsModels, MolecularPressureProtein BindingProtein ConformationProtein DenaturationProtein FoldingProtein Structure, SecondarySpectrophotometry, UltravioletTemperatureCarboxylic Ester Hydrolasespectinesterasecircular dichroismcontact orderdry molten globulehigh pressurekinetic intermediateparallel β-helixprotein foldingrepeat proteinssequential pathway

Identifiers

PMID34439750
PMCPMC8392785
OpenAlexW3183509569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.