Evidence map›Paper›PMID 34439702›Full record

ArticleBrain sciences2021

Rebuilding Body-Brain Interaction from the Vagal Network in Spinal Cord Injuries.

Maria Luisa De Martino, Mina De Bartolo, Erik Leemhuis, Mariella Pazzaglia

Abstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria Luisa De MartinoDepartment of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy.ORCID 0000-0001-6850-6639
Mina De BartoloDepartment of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy.ORCID 0000-0003-3571-9229
Erik LeemhuisDepartment of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy.ORCID 0000-0002-1430-4502
Mariella PazzagliaDepartment of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy.ORCID 0000-0002-9196-7078

Funding

Italian Ministry of Health RF-2018-12365682
6 · The paper itself

Abstract

Spinal cord injuries (SCIs) exert devastating effects on body awareness, leading to the disruption of the transmission of sensory and motor inputs. Researchers have attempted to improve perceived body awareness post-SCI by intervening at the multisensory level, with the integration of somatic sensory and motor signals. However, the contributions of interoceptive-visceral inputs, particularly the potential interaction of motor and interoceptive signals, remain largely unaddressed. The present perspective aims to shed light on the use of interoceptive signals as a significant resource for patients with SCI to experience a complete sense of body awareness. First, we describe interoceptive signals as a significant obstacle preventing such patients from experiencing body awareness. Second, we discuss the multi-level mechanisms associated with the homeostatic stability of the body, which creates a unified, coherent experience of one's self and one's body, including real-time updates. Body awareness can be enhanced by targeting the vagus nerve function by, for example, applying transcutaneous vagus nerve stimulation. This perspective offers a potentially useful insight for researchers and healthcare professionals, allowing them to be better equipped in SCI therapy. This will lead to improved sensory motor and interoceptive signals, a decreased likelihood of developing deafferentation pain, and the successful implementation of modern robotic technologies.

Indexed as

body awarenessinteroceptive signalsneuroplasticitypainspinal cord injurytaVNSvagus nerve

Identifiers

PMID34439702
PMCPMC8391959

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.