ReviewBrain sciences2021
A Systematic Review of Sleep in Patients with Disorders of Consciousness: From Diagnosis to Prognosis.
Review in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Caffeinated Brain Part 2: The Effect of Caffeine on Sleep-Related Electroencephalography (EEG)-A Systematic and Mechanistic Review.Nutrients · 2026Pooled it
- Best Evidence Summary for the Improvement and Management of Disorders of Consciousness in Patients With Severe Brain Injury.Brain and behavior · 2025Pooled it
- The autonomic response following taVNS predicts changes in level of consciousness in DoC patients.Scientific reports · 2025Trial
- Detecting EEG index of arousal in sleeping patients with unresponsive wakefulness syndrome.iScience · 2026Article
- Between Patterns and Predictions: Interpretable Latent EEG Representations for Clinical Insights.medRxiv : the preprint server for health sciences · 2026Article
- Dream content and slow waves benefit prey against predator in a video game confrontation.Scientific reports · 2026Article
- Do individuals with disorders of consciousness dream and mind wander? Implications for improving diagnosis and understanding patient wellbeing.Neuroscience of consciousness · 2025Article
- Exploring bispectral index as an alternative to polysomnography for long-term sleep monitoring in disorders of consciousness.Frontiers in neurology · 2024Article
- Prognosis of consciousness disorders in the intensive care unit.Presse medicale (Paris, France : 1983) · 2023Review
- Sleep in Disorders of Consciousness: A Brief Overview on a Still under Investigated Issue.Brain sciences · 2023Review
- Article
- Conventional and Investigational Approaches Leveraging Clinical EEG for Prognosis in Acute Disorders of Consciousness.Seminars in neurology · 2022Review
- Monitoring Eye Movements Depending on the Type of Visual Stimulus in Patients with Impaired Consciousness Due to Brain Damage.International journal of environmental research and public health · 2022Article
- The Integration of Assistive Technology and Virtual Reality for Assessment and Recovery of Post-coma Patients With Disorders of Consciousness: A New Hypothesis.Frontiers in psychology · 2022Article
- Importance, limits and caveats of the use of "disorders of consciousness" to theorize consciousness.Neuroscience of consciousness · 2021Review
- Neurophysiological predictors of full clinical consciousness recovery in patients with DoC: a retrospective evaluation of the DoC-NP Score.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
With the development of intensive care technology, the number of patients who survive acute severe brain injury has increased significantly. At present, it is difficult to diagnose the patients with disorders of consciousness (DOCs) because motor responses in these patients may be very limited and inconsistent. Electrophysiological criteria, such as event-related potentials or motor imagery, have also been studied to establish a diagnosis and prognosis based on command-following or active paradigms. However, the use of such task-based techniques in DOC patients is methodologically complex and requires careful analysis and interpretation. The present paper focuses on the analysis of sleep patterns for the evaluation of DOC and its relationships with diagnosis and prognosis outcomes. We discuss the concepts of sleep patterns in patients suffering from DOC, identification of this challenging population, and the prognostic value of sleep. The available literature on individuals in an unresponsive wakefulness syndrome (UWS) or minimally conscious state (MCS) following traumatic or nontraumatic severe brain injury is reviewed. We can distinguish patients with different levels of consciousness by studying sleep patients with DOC. Most MCS patients have sleep and wake alternations, sleep spindles and rapid eye movement (REM) sleep, while UWS patients have few EEG changes. A large number of sleep spindles and organized sleep-wake patterns predict better clinical outcomes. It is expected that this review will promote our understanding of sleep EEG in DOC.
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Registered trials
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