Evidence map›Paper›PMID 34439641›Full record

ArticleBrain sciences2021

Influence of Intervertebral Fixation and Segmental Thrust Level on Immediate Post-Spinal Manipulation Trunk Muscle Spindle Response in an Animal Model.

Carla R Lima, Daniel F Martins, Snigdhasree Avatapally, Minjung Cho, Peng Li, William R Reed

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carla R LimaRehabilitation Science Program, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Daniel F MartinsExperimental Neuroscience Laboratory (LaNEx), Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Palhoça, SC 88137-270, Brazil.
Snigdhasree AvatapallyResearch Honors Undergraduate Program, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Minjung ChoResearch Honors Undergraduate Program, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Peng LiSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-9026-9999
William R ReedRehabilitation Science Program, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-4580-485X

Funding

Effect of Lumbar Hypo & Hypermobility on Sensory Responses to Spinal ManipulationK01AT005935 · NCCIH · PALMER COLLEGE OF CHIROPRACTIC · PI REED, WILLIAM RAY · 2010 to 2014
$638k
Proprioceptive mechanisms underlying post-spinal manipulation response in an NGF-induced low back pain modelR21AT010517 · NCCIH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI REED, WILLIAM RAY · 2019 to 2020
$407k
NCCIH NIH HHS K01 AT005935NCCIH NIH HHS K01AT005935NCCIH NIH HHS R21 AT010517NCCIH NIH HHS R21AT010517
6 · The paper itself

Abstract

objectiveTo characterize the effect of unilateral (single and two-level) lumbar facet/zygapophysial joint fixation on paraspinal muscle spindle activity immediately following L4 or L6 high velocity low amplitude spinal manipulation (HVLA-SM) delivered at various thrust durations.

methodsSecondary analysis of immediate (≤2 s) post-HVLA-SM trunk muscle spindle response from two studies involving anesthetized adult cats (

resultsNeither two-level facet joint fixation, nor HVLA-SM segmental level significantly altered immediate post-HVLA-SM spindle discharge at tested thrust durations (FDR > 0.05).

conclusionsTwo-level facet joint fixation failed to alter immediate (≤2 s) post-HVLA-SM spindle discharge when compared to single-level facet joint fixation at any thrust duration. Segmental thrust level did not alter immediate post-HVLA-SM spindle response in two-level facet joint fixation preparations.

Indexed as

catfacet jointhypomobilitymuscle spindlespinal manipulationspinetrunk

Identifiers

PMID34439641
PMCPMC8393701

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.