ArticleBrain sciences2021
Prevalence and Risk Factors for Cognitive Frailty in Aging Hypertensive Patients in China.
Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prevalence and influencing factors of cognitive frailty in Chinese maintenance hemodialysis patients: a systematic review and meta-analysis.BMC nephrology · 2025Pooled it
- Prevalence of cognitive frailty among older adults in China: a systematic review and meta-analysis.BMJ open · 2023Pooled it
- Prevalence and related factors of cognitive frailty in diabetic patients in China: a systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Effects of Baduanjin exercise on cognitive frailty, oxidative stress, and chronic inflammation in older adults with cognitive frailty: a randomized controlled trial.Frontiers in public health · 2024Trial
- The association between handgrip strength, physical, and cognitive function among hospitalized older adults in Tanzania.BMC geriatrics · 2026Article
- Progress in research on cognitive frailty in the older adults: a narrative review.Frontiers in medicine · 2026Review
- A nomogram model for identifying cognitive frailty in elderly patients with chronic diseases: a multicenter cross-sectional study.Frontiers in public health · 2026Observational
- Machine learning algorithms to predict frailty in older adults in China: a cross-sectional study.BMC geriatrics · 2025Article
- Predicting cognitive frailty in community-dwelling older adults: a machine learning approach based on multidomain risk factors.Scientific reports · 2025Article
- The value of radiomics features of white matter hyperintensities in diagnosing cognitive frailty: a study based on T2-FLAIR imaging.BMC medical imaging · 2025Article
- Platelet-to-high-density lipoprotein cholesterol ratio as a predictor of stroke risk: a longitudinal analysis of the China health and retirement longitudinal study.Frontiers in neurology · 2025Article
- Gender differentials in cognitive frailty among older adults in India: a multivariate decomposition approach.Scientific reports · 2024Article
- Prevalence of cognitive frailty and its associated factors in a population of Iranian older adults.Aging clinical and experimental research · 2024Article
- Synergistic effects of cognitive frailty and comorbidities on disability: a community-based longitudinal study.BMC geriatrics · 2024Article
- Role of Cognitive Frailty in Older Adults With Cardiovascular Disease.Journal of the American Heart Association · 2024Review
- Prevalence and modifiable risk factors of cognitive frailty in patients with chronic heart failure in China: a cross-sectional study.BMC cardiovascular disorders · 2024Article
- Latent Subtype of Cognitive Frailty among Multimorbidity Older Adults and Their Association with Social Relationships.Healthcare (Basel, Switzerland) · 2023Article
- Mediating Effect of Loneliness in the Relationship between Depressive Symptoms and Cognitive Frailty in Community-Dwelling Older Adults.Brain sciences · 2022Article
- The Correlation Between Falls and Cognitive Frailty in Elderly Individuals With Hypertension in a Chinese Community.Frontiers in aging neuroscience · 2022Article
Corrections and comments
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4 authors.
Funding
Abstract
Hypertension is one of the most common chronic diseases and a major risk factor for stroke, myocardial infarction and cardiovascular death. Cognitive frailty is an important predictor of all-cause mortality and dementia in aging individuals. Hypertension is closely related to cognitive frailty and these two conditions often coexist in aging individuals. Few studies have explored the relationship between hypertension and cognitive frailty in the Chinese population. This study investigates the epidemiological characteristics of and factors related to cognitive frailty in aging Chinese patients with hypertension. In total, cognitive function, weakness, social support, depression and sociodemographic were assessed in 305 participants aged 60 and over. Univariate and multivariate logistic regression models were constructed. The prevalence of cognitive frailty in aging Chinese hypertensive patients was 9.8% (95% CI = 6.4-13.2%). After adjusting for confounding variables, logistic regression showed that the course of hypertension (6-10 years, OR = 8.588, 95% CI = 1.608-45.859;course of more than 10 years, OR = 9.020, 95%CI = 1.854-43.892), multimorbidity (OR = 11.231, 95% CI = 2.912-43.322), depression (OR = 6.917, 95% CI = 2.424-19.738) and social support (OR = 0.187, 95% CI = 0.071-0.492) were independently associated with cognitive frailty. The prevalence of cognitive frailty in aging patients with hypertension in China should not be ignored. The course of hypertension, multimorbidity and depression are the risk factors of cognitive frailty in the aging population and a better level of social support is the protective factor for cognitive frailty.
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