Evidence map›Paper›PMID 34439604›Full record

ArticleBrain sciences2021

Higher Handgrip Strength Is Linked to Better Cognitive Performance in Chinese Adults with Hypertension.

Shenghua Lu, Fabian Herold, Yanjie Zhang, Yuruo Lei, Arthur F Kramer, Can Jiao, Qian Yu, Scott Doig, Jinming Li, Zhe Yan and 3 more

Abstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shenghua LuHunan Academy of Education Sciences, Changsha 225002, China.
Fabian HeroldResearch Group Neuroprotection, German Center for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, 39120 Magdeburg, Germany.ORCID 0000-0003-3453-090X
Yanjie ZhangHealth and Exercise Science Laboratory, Institute of Sports Science, Seoul National University, Seoul 08826, Korea.ORCID 0000-0002-7964-2326
Yuruo LeiInstitute of Urban Governance, Shenzhen University, Shenzhen 518060, China.
Arthur F KramerCenter for Cognitive and Brain Health, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0001-5870-2724
Can JiaoInstitute of KEEP Collaborative Innovation, Shenzhen University, Shenzhen 518060, China.
Qian YuInstitute of KEEP Collaborative Innovation, Shenzhen University, Shenzhen 518060, China.ORCID 0000-0001-8882-1994
Scott DoigDepartment of Physical Education, Limestone University, Gaffney, SC 29340, USA.
Jinming LiInstitute of KEEP Collaborative Innovation, Shenzhen University, Shenzhen 518060, China.ORCID 0000-0003-0569-0824
Zhe YanInstitute of KEEP Collaborative Innovation, Shenzhen University, Shenzhen 518060, China.
Jin KuangInstitute of KEEP Collaborative Innovation, Shenzhen University, Shenzhen 518060, China.
Ting WangInstitute of KEEP Collaborative Innovation, Shenzhen University, Shenzhen 518060, China.ORCID 0000-0001-8357-0356
Liye ZouInstitute of KEEP Collaborative Innovation, Shenzhen University, Shenzhen 518060, China.ORCID 0000-0001-6411-5710

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThere is growing evidence that in adults, higher levels of handgrip strength (HGS) are linked to better cognitive performance. However, the relationship between HGS and cognitive performance has not been sufficiently investigated in special cohorts, such as individuals with hypertension who have an intrinsically higher risk of cognitive decline. Thus, the purpose of this study was to examine the relationship between HGS and cognitive performance in adults with hypertension using data from the Global Ageing and Adult Health Survey (SAGE).

methodsA total of 4486 Chinese adults with hypertension from the SAGE were included in this study. Absolute handgrip strength (aHGS in kilograms) was measured using a handheld electronic dynamometer, and cognitive performance was assessed in the domains of short-term memory, delayed memory, and language ability. Multiple linear regression models were fitted to examine the association between relative handgrip strength (rHGS; aHGS divided by body mass index) and measures of cognitive performance.

resultsOverall, higher levels of rHGS were associated with higher scores in short-term memory (β = 0.20) and language (β = 0.63) compared with the lowest tertiles of rHGS. In male participants, higher HGS was associated with higher scores in short-term memory (β = 0.31), language (β = 0.64), and delayed memory (β = 0.22). There were no associations between rHGS and cognitive performance measures in females.

conclusionWe observed that a higher level of rHGS was associated with better cognitive performance among hypertensive male individuals. Further studies are needed to investigate the neurobiological mechanisms, including sex-specific differences driving the relationship between measures of HGS and cognitive performance in individuals with hypertension.

Indexed as

Chinacognitionhandgrip strengthhypertension

Identifiers

PMID34439604
PMCPMC8391417

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.