Evidence map›Paper›PMID 34439580›Full record

ArticleBrain sciences2021

Comparing the Impact of Multi-Session Left Dorsolateral Prefrontal and Primary Motor Cortex Neuronavigated Repetitive Transcranial Magnetic Stimulation (nrTMS) on Chronic Pain Patients.

Sascha Freigang, Christian Lehner, Shane M Fresnoza, Kariem Mahdy Ali, Elisabeth Hlavka, Annika Eitler, Istvan Szilagyi, Helmar Bornemann-Cimenti, Hannes Deutschmann, Gernot Reishofer and 6 more

Abstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Intermittent theta-burst stimulation to enhance physical therapy in Parkinson's disease: The STEP-PD randomized trial.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Trial
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  10. Cortical stimulation for chronic pain: from anecdote to evidence.European journal of physical and rehabilitation medicine · 2022
    Review
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  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sascha FreigangDepartment of Neurosurgery, Medical University Graz, 8036 Graz, Austria.ORCID 0000-0001-8298-1663
Christian LehnerDepartment of Neurosurgery, Medical University Graz, 8036 Graz, Austria.
Shane M FresnozaInstitute of Psychology, University of Graz, 8010 Graz, Austria.ORCID 0000-0002-9938-2285
Kariem Mahdy AliDepartment of Neurosurgery, Medical University Graz, 8036 Graz, Austria.
Elisabeth HlavkaDepartment of Neurosurgery, Medical University Graz, 8036 Graz, Austria.
Annika EitlerDepartment of Neurosurgery, Medical University Graz, 8036 Graz, Austria.
Istvan SzilagyiDepartment of Paediatric Surgery, Medical University Graz, 8036 Graz, Austria.
Helmar Bornemann-CimentiDepartment of Anaesthesiology, Critical Care and Pain Medicine, Medical University Graz, 8036 Graz, Austria.
Hannes DeutschmannDepartment of Radiology, Clinical Division of Neuroradiology, Vascular and Interventionial Radiology, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0003-4552-699X
Gernot ReishoferDepartment of Radiology, Clinical Division of Neuroradiology, Vascular and Interventionial Radiology, Medical University of Graz, 8036 Graz, Austria.
Anže BerlecDepartment of Neurosurgery, Medical University Graz, 8036 Graz, Austria.
Senta Kurschel-LacknerDepartment of Neurosurgery, Medical University Graz, 8036 Graz, Austria.
Antonio ValentinDepartment of Basic & Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 9RT, UK.
Bernhard SutterDepartment of Neurosurgery, Medical University Graz, 8036 Graz, Austria.
Karla ZaarDepartment of Neurosurgery, Medical University Graz, 8036 Graz, Austria.
Michael MokryDepartment of Neurosurgery, Medical University Graz, 8036 Graz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Repetitive transcranial stimulation (rTMS) has been shown to produce an analgesic effect and therefore has a potential for treating chronic refractory pain. However, previous studies used various stimulation parameters (including cortical targets), and the best stimulation protocol is not yet identified. The present study investigated the effects of multi-session 20 Hz (2000 pulses) and 5 Hz (1800 pulses) rTMS stimulation of left motor cortex (M1-group) and left dorsolateral prefrontal cortex (DLPFC-group), respectively. The M1-group (

Indexed as

chronic paindorsolateral prefrontal cortexlow back painneuromodulationprimary motor cortexrepetitive transcranial magnetic stimulation

Identifiers

PMID34439580
PMCPMC8391537

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.