Evidence map›Paper›PMID 34439541›Full record

ReviewAntioxidants (Basel, Switzerland)2021

Statins' Regulation of the Virulence Factors of

Ting-Yu Lin, Wen-Hsi Lan, Ya-Fang Chiu, Chun-Lung Feng, Cheng-Hsun Chiu, Chia-Jung Kuo, Chih-Ho Lai

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Unveiling the Antibacterial Properties of Statins: AnAdvances in pharmacological and pharmaceutical sciences · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ting-Yu LinSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Wen-Hsi LanSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Ya-Fang ChiuSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Chun-Lung FengDivision of Gastroenterology and Hepatology, Department of Internal Medicine, China Medical University Hsinchu Hospital, Hsinchu 30272, Taiwan.
Cheng-Hsun ChiuSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Chia-Jung KuoSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Chih-Ho LaiResearch Center for Emerging Viral, Infections Department of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0001-7145-784X
Chang Gung University · TWAsia University · TWChina Medical University · TW

Funding

Chang Gung Memorial Hospital, Linkou CMRPD1I0061-3, CMRPD1J0021-3, CMRPD1K0361, and BMRPE90Ministry of Science and Technology, Taiwan 109-2320-B-182-025-MY3, 109-2320-B-182-029-MY3, and 109-2622-B-182-002
6 · The paper itself

Abstract

Conventionally, statins are used to treat high cholesterol levels. They exhibit pleiotropic effects, such as the prevention of cardiovascular disease and decreased cancer mortality. Gastric cancer (GC) is one of the most common cancers, ranking as the third leading global cause of cancer-related deaths, and is mainly attributed to chronic

Indexed as

cholesterolgastric cancerHelicobacter pylorireactive oxygen speciesstatin

Identifiers

PMID34439541
PMCPMC8389206
OpenAlexW3194786435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.