Evidence map›Paper›PMID 34439488›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Yana Shaulov, Lotem Sarid, Meirav Trebicz-Geffen, Serge Ankri

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Microbiology spectrum · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Structure ofInternational journal of molecular sciences · 2023
    Article
  7. Article
  8. Article
  9. Insights into the Mechanisms ofAntioxidants (Basel, Switzerland) · 2022
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yana ShaulovDepartment of Molecular Microbiology, Ruth and Bruce Rappaport Faculty of Medicine, Technion, 31096 Haifa, Israel.
Lotem SaridDepartment of Molecular Microbiology, Ruth and Bruce Rappaport Faculty of Medicine, Technion, 31096 Haifa, Israel.ORCID 0000-0001-7097-5258
Meirav Trebicz-GeffenDepartment of Molecular Microbiology, Ruth and Bruce Rappaport Faculty of Medicine, Technion, 31096 Haifa, Israel.
Serge AnkriDepartment of Molecular Microbiology, Ruth and Bruce Rappaport Faculty of Medicine, Technion, 31096 Haifa, Israel.ORCID 0000-0002-8775-1557

Funding

ISF-NRF 3208/19Israel Science Foundation 260/16Niedersachsen ZN3454United States-Israel Binational Science Foundation 2015211
6 · The paper itself

Abstract

Auranofin (AF), an antirheumatic agent, targets mammalian thioredoxin reductase (TrxR), an important enzyme controlling redox homeostasis. AF is also highly effective against a diversity of pathogenic bacteria and protozoan parasites. Here, we report on the resistance of the parasite

Indexed as

auranofindrug resistanceEntamoeba histolyticaredoxomicsthioredoxin reductasetranscriptomics

Identifiers

PMID34439488
PMCPMC8389260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.