Evidence map›Paper›PMID 34439483›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Anthocyanins Promote Learning through Modulation of Synaptic Plasticity Related Proteins in an Animal Model of Ageing.

David Vauzour, Catarina Rendeiro, Alfonsina D'Amato, Pierre Waffo-Téguo, Tristan Richard, Jean Michel Mérillon, Matthew G Pontifex, Emily Connell, Michael Müller, Laurie T Butler and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

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  16. Chronic Consumption of Cranberries (Frontiers in nutrition · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

David VauzourFaculty of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich NR4 7UQ, UK.ORCID 0000-0001-5952-8756
Catarina RendeiroSchool of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Alfonsina D'AmatoDepartment of Pharmaceutical Sciences, University of Milan, 20133 Milan, Italy.ORCID 0000-0002-8147-7235
Pierre Waffo-TéguoUFR des Sciences Pharmaceutiques, Unité de Recherche Œnologie EA 4577, University of Bordeaux, USC 1366 INRA, Equipe Molécules d'Intérêt Biologique, 210 Chemin de Leysotte, F-33882 Villenave d'Ornon, France.
Tristan RichardUFR des Sciences Pharmaceutiques, Unité de Recherche Œnologie EA 4577, University of Bordeaux, USC 1366 INRA, Equipe Molécules d'Intérêt Biologique, 210 Chemin de Leysotte, F-33882 Villenave d'Ornon, France.ORCID 0000-0002-5308-8697
Jean Michel MérillonUFR des Sciences Pharmaceutiques, Unité de Recherche Œnologie EA 4577, University of Bordeaux, USC 1366 INRA, Equipe Molécules d'Intérêt Biologique, 210 Chemin de Leysotte, F-33882 Villenave d'Ornon, France.
Matthew G PontifexFaculty of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich NR4 7UQ, UK.
Emily ConnellFaculty of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich NR4 7UQ, UK.
Michael MüllerFaculty of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich NR4 7UQ, UK.ORCID 0000-0002-5930-9905
Laurie T ButlerFaculty of Science and Engineering, Anglia Ruskin University, Cambridge CB1 1PT, UK.
Claire M WilliamsSchool of Psychology and Clinical Language Sciences, University of Reading, Reading RG6 6AL, UK.ORCID 0000-0003-4452-671X
Jeremy P E SpencerMolecular Nutrition Group, Department of Food and Nutritional Sciences, School of Chemistry, Food and Pharmacy, University of Reading, Reading RG6 6AP, UK.
University of East Anglia · GBUniversité de Bordeaux · FRUniversity of Reading · GBAnglia Ruskin University · GBUniversity of Birmingham · GBUniversity of Milan · IT

Funding

Biotechnology and Biological Sciences Research Council BB/F008953/1
6 · The paper itself

Abstract

Anthocyanin-rich foods, such as berries, reportedly ameliorate age-related cognitive deficits in both animals and humans. Despite this, investigation into the mechanisms which underpin anthocyanin-mediated learning and memory benefits remains relatively limited. The present study investigates the effects of anthocyanin intake on a spatial working memory paradigm, assessed via the cross-maze apparatus, and relates behavioural test performance to underlying molecular mechanisms. Six-week supplementation with pure anthocyanins (2%

Indexed as

braincognitionflavonoidsneuroprotectionsignalling

Identifiers

PMID34439483
PMCPMC8388918
OpenAlexW3188997258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.