Evidence map›Paper›PMID 34439376›Full record

ArticleCancers2021

Validating Methylated HOXA9 in Bronchial Lavage as a Diagnostic Tool in Patients Suspected of Lung Cancer.

Sara W C Wen, Rikke F Andersen, Kristian Rasmussen, Caroline Brenner Thomsen, Torben Frøstrup Hansen, Line Nederby, Henrik Hager, Anders Jakobsen, Ole Hilberg

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Circulating methylatedOncology letters · 2024
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sara W C WenDepartment of Oncology, Vejle Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark.ORCID 0000-0003-3755-0922
Rikke F AndersenDepartment of Clinical Biochemistry, Vejle Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark.ORCID 0000-0002-5894-7745
Kristian RasmussenDepartment of Internal Medicine, Vejle Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark.
Caroline Brenner ThomsenDepartment of Oncology, Vejle Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark.ORCID 0000-0003-4481-6274
Torben Frøstrup HansenDepartment of Oncology, Vejle Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark.ORCID 0000-0001-7476-671X
Line NederbyDepartment of Clinical Biochemistry, Vejle Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark.
Henrik HagerInstitute of Regional Health Research, University of Southern Denmark, 5230 Odense M, Denmark.
Anders JakobsenDepartment of Oncology, Vejle Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark.ORCID 0000-0003-2110-2615
Ole HilbergInstitute of Regional Health Research, University of Southern Denmark, 5230 Odense M, Denmark.

Funding

Department of Oncology, Vejle Hospital NumberRegion of Southern Denmark Number
6 · The paper itself

Abstract

Diagnosing lung cancer requires invasive procedures with high risk of complications. Methylated tumor DNA in bronchial lavage has previously shown potential as a diagnostic biomarker. We aimed to develop and validate methylated

Indexed as

circulating tumor DNAlung cancermethylated HOXA9

Identifiers

PMID34439376
PMCPMC8393370

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.