Evidence map›Paper›PMID 34439314›Full record

ArticleCancers2021

SARAF and EFHB Modulate Store-Operated Ca

Isaac Jardin, Joel Nieto-Felipe, Sandra Alvarado, Raquel Diez-Bello, Jose J Lopez, Ginés M Salido, Tarik Smani, Juan A Rosado

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Isaac JardinDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.ORCID 0000-0003-4575-8264
Joel Nieto-FelipeDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.
Sandra AlvaradoDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.
Raquel Diez-BelloDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.
Jose J LopezDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.ORCID 0000-0002-5234-1478
Ginés M SalidoDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.ORCID 0000-0002-8687-2445
Tarik SmaniDepartment of Medical Physiology and Biophysic, Institute of Biomedicine of Sevilla, 41013 Sevilla, Spain.ORCID 0000-0002-1877-7438
Juan A RosadoDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.ORCID 0000-0002-9749-2325

Funding

Junta de Extremadura GR18061Junta de Extremadura IB20007Ministerio de Ciencia e Innovación PID2019-104084GB-C21Ministerio de Ciencia e Innovación PID2019-104084GB-C22
6 · The paper itself

Abstract

Breast cancer is among the most common malignancies in women. From the molecular point of view, breast cancer can be grouped into different categories, including the luminal (estrogen receptor positive (ER+)) and triple negative subtypes, which show distinctive features and, thus, are sensitive to different therapies. Breast cancer cells are strongly dependent on Ca

Indexed as

breast cancer cellscalcium entryEFHBmigrationSARAFviability

Identifiers

PMID34439314
PMCPMC8393677

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.