Evidence map›Paper›PMID 34439221›Full record

ArticleCancers2021

Magnetic Resonance Relaxometry for Tumor Cell Density Imaging for Glioma: An Exploratory Study via

Manabu Kinoshita, Masato Uchikoshi, Souichiro Tateishi, Shohei Miyazaki, Mio Sakai, Tomohiko Ozaki, Katsunori Asai, Yuya Fujita, Takahiro Matsuhashi, Yonehiro Kanemura and 5 more

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. A Histopathologic Correlation Study Evaluating Glymphatic Function in Brain Tumors by Multiparametric MRI.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Neuro-oncology advances
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Manabu KinoshitaDepartment of Neurosurgery, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku 541-8567, Japan.ORCID 0000-0001-7923-6902
Masato UchikoshiDepartment of Neurosurgery, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku 541-8567, Japan.
Souichiro TateishiDepartment of Diagnostic and Interventional Radiology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku 541-8567, Japan.
Shohei MiyazakiDepartment of Diagnostic and Interventional Radiology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku 541-8567, Japan.
Mio SakaiDepartment of Diagnostic and Interventional Radiology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku 541-8567, Japan.
Tomohiko OzakiDepartment of Neurosurgery, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku 541-8567, Japan.
Katsunori AsaiDepartment of Neurosurgery, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku 541-8567, Japan.
Yuya FujitaDepartment of Neurosurgery, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku 541-8567, Japan.ORCID 0000-0001-8155-6040
Takahiro MatsuhashiDepartment of Neurosurgery, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku 541-8567, Japan.
Yonehiro KanemuraDepartment of Biomedical Research and Innovation, Institute for Clinical Research, National Hospital Organization Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku 540-0006, Japan.
Eku ShimosegawaDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita 565-0871, Japan.ORCID 0000-0003-4373-1623
Jun HatazawaDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita 565-0871, Japan.
Shin-Ichi NakatsukaDepartment of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku 541-8567, Japan.
Haruhiko KishimaDepartment of Neurosurgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita 565-0871, Japan.ORCID 0000-0002-9041-2337
Katsuyuki NakanishiDepartment of Diagnostic and Interventional Radiology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku 541-8567, Japan.

Funding

Japan Society for the Promotion of Science 19K09526MSD Life Science Foundation, Public Interest Incorporated Foundation NoneTakeda Science Foundation NoneThe foundation for the prevention of cancer and cardiovascular diseases None
6 · The paper itself

Abstract

One of the most crucial yet challenging issues for glioma patient care is visualizing non-contrast-enhancing tumor regions. In this study, to test the hypothesis that quantitative magnetic resonance relaxometry reflects glioma tumor load within tissue and that it can be an imaging surrogate for visualizing non-contrast-enhancing tumors, we investigated the correlation between T1- and T2-weighted relaxation times, apparent diffusion coefficient (ADC) on magnetic resonance imaging, and

Indexed as

11C-methionine positron emission tomography (MET-PET)magnetic resonance imaging (MRI)malignant gliomanon-contrast-enhancing tumorrelaxometry

Identifiers

PMID34439221
PMCPMC8393497

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.