Evidence map›Paper›PMID 34439188›Full record

ArticleCancers2021

Simultaneous Recording of the Uptake and Conversion of Glucose and Choline in Tumors by Deuterium Metabolic Imaging.

Andor Veltien, Jack van Asten, Niveditha Ravichandran, Robin A de Graaf, Henk M De Feyter, Egbert Oosterwijk, Arend Heerschap

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Review
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  11. Molecular Imaging: Unveiling Metabolic Abnormalities in Pancreatic Cancer.International journal of molecular sciences · 2025
    Review
  12. Article
  13. Article
  14. A Genetically Engineered Reporter System Designed forJournal of the American Chemical Society · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Andor VeltienDepartment of Medical Imaging (Radiology), Radboud University Medical Centre, 6500HB Nijmegen, The Netherlands.ORCID 0000-0002-8090-5445
Jack van AstenDepartment of Medical Imaging (Radiology), Radboud University Medical Centre, 6500HB Nijmegen, The Netherlands.
Niveditha RavichandranDepartment of Medical Imaging (Radiology), Radboud University Medical Centre, 6500HB Nijmegen, The Netherlands.
Robin A de GraafDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT 06520-8043, USA.
Henk M De FeyterDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT 06520-8043, USA.
Egbert OosterwijkDepartment of Urology, Radboud University Medical Centre, 6500HB Nijmegen, The Netherlands.
Arend HeerschapDepartment of Medical Imaging (Radiology), Radboud University Medical Centre, 6500HB Nijmegen, The Netherlands.
Radboud University Nijmegen · NLYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Increased glucose and choline uptake are hallmarks of cancer. We investigated whether the uptake and conversion of [

Indexed as

2Hcholinedeuterium metabolic imagingglucoseMRItumor

Identifiers

PMID34439188
PMCPMC8394025
OpenAlexW3192286578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.