Evidence map›Paper›PMID 34439117›Full record

ReviewCancers2021

Different Approaches for Case-Mix Adjustment of Patient-Reported Outcomes to Compare Healthcare Providers-Methodological Results of a Systematic Review.

Nora Tabea Sibert, Holger Pfaff, Clara Breidenbach, Simone Wesselmann, Christoph Kowalski

Abstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Factors independently associated with in-hospital HRQoL in adults treated at a high-complexity institution in a middle-income country.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nora Tabea SibertGerman Cancer Society, Kuno-Fischer-Str. 8, 14507 Berlin, Germany.
Holger PfaffInstitute of Medical Sociology, Health Services Research, and Rehabilitation Science, Faculty of Medicine and University Hospital Cologne, Faculty of Human Sciences, University of Cologne, 50933 Cologne, Germany.ORCID 0000-0001-9154-6575
Clara BreidenbachGerman Cancer Society, Kuno-Fischer-Str. 8, 14507 Berlin, Germany.
Simone WesselmannGerman Cancer Society, Kuno-Fischer-Str. 8, 14507 Berlin, Germany.
Christoph KowalskiGerman Cancer Society, Kuno-Fischer-Str. 8, 14507 Berlin, Germany.ORCID 0000-0002-7438-4321

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patient-reported outcomes (PROs) are increasingly being used to compare the quality of outcomes between different healthcare providers (medical practices, hospitals, rehabilitation facilities). However, such comparisons can only be fair if differences in the case-mix between different types of provider are taken into account. This can be achieved with adequate statistical case-mix adjustment (CMA). To date, there is a lack of overview studies on current CMA methods for PROs. The aim of this study was to investigate which approaches are currently used to report and examine PROs for case-mix-adjusted comparison between providers. A systematic MEDLINE literature search was conducted (February 2021). The results were examined by two reviewers. Articles were included if they compared (a) different healthcare providers using (b) case-mix-adjusted (c) patient-reported outcomes (all AND conditions). From 640 hits obtained, 11 articles were included in the analysis. A wide variety of patient characteristics were used as adjustors, and baseline PRO scores and basic sociodemographic and clinical information were included in all models. Overall, the adjustment models used vary considerably. This evaluation is an initial attempt to systematically investigate different CMA approaches for PROs. As a standardized approach has not yet been established, we suggest creating a consensus-based methodological guideline for case-mix adjustment of PROs.

Indexed as

case-mix adjustmenthealthcare provider comparisonpatient-reported outcomesquality improvement

Identifiers

PMID34439117
PMCPMC8392243

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.