ArticleCancers2021
Predictors of Invasive Adenocarcinomas among Pure Ground-Glass Nodules Less Than 2 cm in Diameter.
Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Multifocal micronodular pneumocyte hyperplasia in the absence of tuberous sclerosis complex: A case report.Radiology case reports · 2026Article
- Artificial intelligence-based density proportion analysis in predicting the invasiveness of neoplastic ground-glass nodules.Translational lung cancer research · 2026Article
- Development of a CT-based comprehensive model with deep learning for differentiating pathological types of pulmonary ground-glass nodules.Frontiers in medicine · 2026Article
- Deep learning for Three-Class Classification of ground-glass nodules on non-enhanced chest CT: A multicenter comparative study of CNN architectures.European journal of radiology open · 2025Article
- Predicting pathological subtypes of pure ground-glass nodules using Swin Transformer deep learning model.Insights into imaging · 2025Article
- Lesion-vessel spatial relationship: a significant indicator for differentiation and evaluation of pulmonary ground-glass nodules.Quantitative imaging in medicine and surgery · 2025Article
- Prediction and analysis of the tumor invasiveness of pulmonary ground-glass nodules based on metabolomics.Clinical and experimental medicine · 2024Article
- CT and MR Imaging in Colorectal Carcinoma: A Tool for Diagnosis, Staging, Response Evaluation, and Follow-Up.South Asian journal of cancer · 2024Review
- Evaluation of the invasiveness of pure ground-glass nodules based on dual-head ResNet technique.BMC cancer · 2024Article
- Artificial intelligence-measured nodule mass for determining the invasiveness of neoplastic ground glass nodules.Quantitative imaging in medicine and surgery · 2024Article
- Image quality and detection efficacy of zero echo time magnetic resonance imaging on Lung-RADS 2 pulmonary ground-glass nodules in comparison to thin-slice fat-saturated T2-weighted imaging.Journal of thoracic disease · 2024Article
- Construction and validation of a risk score system for diagnosing invasive adenocarcinoma presenting as pulmonary pure ground-glass nodules: a multi-center cohort study in China.Quantitative imaging in medicine and surgery · 2024Article
- A nomogram combining CT-based radiomic features with clinical features for the differentiation of benign and malignant cystic pulmonary nodules.Journal of cardiothoracic surgery · 2024Article
- Discrimination of invasive lung adenocarcinoma from Lung-RADS category 2 nonsolid nodules through visual assessment: a retrospective study.European radiology · 2024Article
- Clinical Outcomes of Resected Pure Ground-Glass, Heterogeneous Ground-Glass, and Part-Solid Pulmonary Nodules.AJR. American journal of roentgenology · 2024Article
- Bubble-like lucency in pulmonary ground glass nodules on computed tomography: a specific pattern of air-containing space for diagnosing neoplastic lesions.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- The predictive value of computed tomography value on high-resolution images in differentiating invasive from indolent lung adenocarcinoma.Translational cancer research · 2024Article
- Predicting the Invasiveness of Pulmonary Adenocarcinomas in Pure Ground-Glass Nodules Using the Nodule Diameter: A Systematic Review, Meta-Analysis, and Validation in an Independent Cohort.Diagnostics (Basel, Switzerland) · 2024Review
- [Establishment and Verification of Benign and Malignant Prediction Model of Subcentimeter Pulmonary Ground Glass Nodules Based on HRCT].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2023Article
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8 authors.
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Abstract
Benign lesions, atypical adenomatous hyperplasia (AAH), and malignancies such as adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), and invasive adenocarcinoma (IA) may feature a pure ground-glass nodule (pGGN) on a thin-slide computed tomography (CT) image. According to the World Health Organization (WHO) classification for lung cancer, the prognosis of patients with IA is worse than those with AIS and MIA. It is relatively risky to perform a core needle biopsy of a pGGN less than 2 cm to obtain a reliable pathological diagnosis. The early and adequate management of patients with IA may provide a favorable prognosis. This study aimed to disclose suggestive signs of CT to accurately predict IA among the pGGNs. A total of 181 pGGNs of less than 2 cm, in 171 patients who had preoperative CT-guided localization for surgical excision of a lung nodule between December 2013 and August 2019, were enrolled. All had CT images of 0.625 mm slice thickness during CT-guided intervention to confirm that the nodules were purely ground glass. The clinical data, CT images, and pathological reports of those 171 patients were reviewed. The CT findings of pGGNs including the location, the maximal diameter in the long axis (size-L), the maximal short axis diameter perpendicular to the size-L (size-S), and the mean value of long and short axis diameters (size-M), internal content, shape, interface, margin, lobulation, spiculation, air cavity, vessel relationship, and pleural retraction were recorded and analyzed. The final pathological diagnoses of the 181 pGGNs comprised 29 benign nodules, 14 AAHs, 25 AISs, 55 MIAs, and 58 IAs. Statistical analysis showed that there were significant differences among the aforementioned five groups with respect to size-L, size-S, and size-M (
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